Functional Intermuscular Reduction of Spasticity (MS-FIRST)
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|ClinicalTrials.gov Identifier: NCT04403594|
Recruitment Status : Recruiting
First Posted : May 27, 2020
Last Update Posted : May 27, 2020
|Condition or disease||Intervention/treatment|
|Multiple Sclerosis||Other: dry needling|
|Study Type :||Observational|
|Estimated Enrollment :||16 participants|
|Official Title:||Functional Intermuscular Reduction of SpasTicity in MS (MS-FIRST)|
|Actual Study Start Date :||August 19, 2019|
|Estimated Primary Completion Date :||December 18, 2020|
|Estimated Study Completion Date :||December 18, 2020|
MS with spasticity of one lower extremity
A person diagnosed with Multiple Sclerosis and spasticty of one lower extremity. The person must be able to walk 25 feet and cannot have had Botox in the lower extremity on the last 6 months.
Other: dry needling
dry needling followed by functional electrical stimulation and treadmill training
Other Name: functional electrical stimulation
- 6 minute walk test [ Time Frame: up to 7 weeks ]distance walked over 6 minutes assessed at the start of the study and after 6 weeks.
- 25-foot walk [ Time Frame: up to 7 weeks ]time to walk 25 feet assessed at the start of the study and after 6 weeks.
- Berg Balance Scale [ Time Frame: up to 7 weeks ]Balance test conducted at the start of the study and after 6 weeks.
- Modified Fatigue Impact Scale [ Time Frame: up to 7 weeks ]patient-reported questionnaire collected at the start of the study and after 6 weeks.
- Toe taps on force plate [ Time Frame: up to 7 weeks ]number of toe taps in 10 seconds counted at the start of the study and after 6 weeks.
- EMG data of both lower extremities [ Time Frame: up to 7 weeks ]Electromyography (EMG) will be conducted at the start of the study and after 6 weeks. EMG is an electrodiagnostic technique for evaluating and recording the electrical activity produced by skeletal muscles. This is completed using electrodes that are placed on the skin, which detects the electric potential generated by muscle cells when these cells are electrically or neurologically activated. These action potentials are measured and recorded on a computer.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT04403594
|Contact: Bobbette Miller, DPTfirstname.lastname@example.org|
|Contact: Shirley James, PhD||405-271-2132 ext email@example.com|
|Principal Investigator:||Shirley James, PhD||University of Oklahoma|