Petechiae In Children (PIC) Study: Defining A Clinical Decision Rule for The Management Of Fever and Non-Blanching Rashes In Children Including The Role Of Point Of Care Testing For Procalcitonin & Neisseria Meningitidis DNA. (PIC)
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|ClinicalTrials.gov Identifier: NCT03378258|
Recruitment Status : Recruiting
First Posted : December 19, 2017
Last Update Posted : September 28, 2018
A fever and a non-blanching rash is a relatively common reason for a child to attend an emergency department. A fever and a non-blanching rash can be an early sign of a life-threatening infection known as meningococcal disease. The aim of the PIC study is to determine how best to diagnose early meningococcal disease in children.
In particular the investigators are interested in researching how quick bedside tests can be used to do this.
|Condition or disease|
|Meningitis, Meningococcal Meningococcal Sepsis Meningococcal Disease Meningococcal Infections Sepsis Meningitis|
A fever an a non-blanching rash is a relatively common presentation the the emergency department. A minority of children with a fever and a non-blanching rash with have a life-threatening infection. Currently it is very difficult to determine those children that require urgent treatment from those that have a simple viral illness.
The aim of the PIC study is to research how to better diagnose those serious infections earlier.
Data from the study will be used to test the effectiveness of current practice and to identify areas where current practice could be improved.
|Study Type :||Observational|
|Estimated Enrollment :||1000 participants|
|Official Title:||Petechiae In Children (PIC) Study|
|Actual Study Start Date :||November 9, 2017|
|Estimated Primary Completion Date :||August 1, 2020|
|Estimated Study Completion Date :||August 1, 2020|
- Confirmation of meningococcal infection [ Time Frame: 72 hours from testing ]Blood and Cerebrospinal fluid (CSF) culture or quantitative Polymerase Chain Reaction (PCR) will be used to confirm meningococcal infection
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03378258
|Contact: Thomas Waterfieldfirstname.lastname@example.org|
|Contact: Michael D Shieldsemail@example.com|
|Royal Belfast Hospital for Sick Children||Recruiting|
|Belfast, Northern Ireland, United Kingdom, BT126BE|
|Contact: Thomas Waterfield 02890633755 firstname.lastname@example.org|
|Contact: Michael Shields 02890633755 email@example.com|
|Principal Investigator:||MIchael D Shields||Queen's University, Belfast|