Working…
ClinicalTrials.gov
ClinicalTrials.gov Menu

Investigating Accelerated Learning and Memory in Healthy Subjects Using a Face Name Memory Task

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
 
ClinicalTrials.gov Identifier: NCT03309072
Recruitment Status : Active, not recruiting
First Posted : October 13, 2017
Results First Posted : September 11, 2020
Last Update Posted : September 11, 2020
Sponsor:
Information provided by (Responsible Party):
Sven Vanneste, The University of Texas at Dallas

Brief Summary:
The purpose of this study is to investigate whether we can accelerate learning and improve associative memory performance in healthy subjects by applying transcranial Direct Current Stimulation (tDCS) during a Face Name memory task.

Condition or disease Intervention/treatment Phase
Healthy Adults Device: tDCS Device: sham tDCS Not Applicable

Detailed Description:

Associative memory refers to remembering the association between two items, such as a face and a name or a word in English and the same word in another language. It is not only important for learning, but it is also one of the first aspects of memory performance that is impacted by aging and by Alzheimer׳s disease. For decades, neuroscientists have investigated associative learning and memory and ways to accelerate and enhance associative learning and memory.

Transcranial Direct Current stimulation (tDCS) is a non-invasive and painless electrical stimulation technique that has demonstrated to accelerate learning and improve memory in some studies. To investigate whether we can accelerate learning and improve associative memory using tDCS, we will compare the performance in a Face Name Associate memory task from 2 groups. The first group will get active tDCS during the study phase of the Face Name Memory task, whereas the second group will get sham tDCS during the study phase of the task.

Layout table for study information
Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 30 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Intervention Model Description: Participants will be randomly assigned to one of two groups: (1) active tDCS with Face Name associate memory task (2) sham tDCS with Face Name associate memory task
Masking: Double (Participant, Outcomes Assessor)
Primary Purpose: Basic Science
Official Title: Investigating Accelerated Learning and Memory in Healthy Subjects Using a Face Name Memory Task
Actual Study Start Date : September 27, 2017
Actual Primary Completion Date : June 12, 2018
Estimated Study Completion Date : May 9, 2023

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Memory

Arm Intervention/treatment
Experimental: active tDCS
active tDCS with Face Name associate Memory task
Device: tDCS
active tDCS

Sham Comparator: sham tDCS
sham tDCS with Face Name associate Memory task
Device: sham tDCS
sham tDCS




Primary Outcome Measures :
  1. Associative Memory Assessed by a Face Name Associate Memory Experiment [ Time Frame: Associate Memory is assessed after a 10 minutes break following the study phase ]

    All participants performed a face memory task .The face stimuli consisted of 120 grayscale pictures of human faces. Only faces with a neutral expression facing forward were selected. Half of the faces were male, and the other half were female. The face-name association memory task was divided into (1) an encoding phase, (2) a consolidation phase, and (3) a retrieval phase. During the encoding phase, participants studied 60 successively presented face-name pairs and were instructed to assess their gender to keep them focused to the task. The encoding phase was followed by a consolidation phase where participants were instructed to "sit still, relax, and think about nothing in particular" for 10 minutes, During the retrieval phase, participants were presented with 60 old and 60 new faces and were instructed to assess whether they have seen this face during the encoding phase.

    The outcome was the percent of Correct Name to Face Matches




Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Layout table for eligibility information
Ages Eligible for Study:   18 Years to 35 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Age: 18-35 years
  • Native English Speaker

Exclusion Criteria:

  • History of severe head injuries, epileptic insults, or heart disease.
  • Severe psychiatric disorders and severe untreated medical problems.
  • Contraindications for tDCS (pregnant women, implanted devices)

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03309072


Locations
Layout table for location information
United States, Texas
The University of Texas of Dallas
Richardson, Texas, United States, 75080
Sponsors and Collaborators
The University of Texas at Dallas
Investigators
Layout table for investigator information
Principal Investigator: Sven Vanneste, PhD The University of Texas at Dallas
  Study Documents (Full-Text)

Documents provided by Sven Vanneste, The University of Texas at Dallas:
Study Protocol: Protocol 17-96  [PDF] January 1, 2016
No Statistical Analysis Plan (SAP) exists for this study.

Layout table for additonal information
Responsible Party: Sven Vanneste, Associate professor, The University of Texas at Dallas
ClinicalTrials.gov Identifier: NCT03309072    
Other Study ID Numbers: 17-96
First Posted: October 13, 2017    Key Record Dates
Results First Posted: September 11, 2020
Last Update Posted: September 11, 2020
Last Verified: August 2020
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: No

Layout table for additional information
Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: Yes
Keywords provided by Sven Vanneste, The University of Texas at Dallas:
transcranial Direct Current Stimulation (tDCS)
accelerated learning
memory