Headache Inducing Effect of Cromakalim in Migraine Patients
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|ClinicalTrials.gov Identifier: NCT03228355|
Recruitment Status : Completed
First Posted : July 24, 2017
Last Update Posted : June 19, 2018
|Condition or disease||Intervention/treatment||Phase|
|Headache, Migraine||Drug: Levcromakalim Drug: Saline||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||16 participants|
|Intervention Model:||Crossover Assignment|
|Masking:||Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)|
|Official Title:||The Effects of Levcromakalim on Cerebral Hemodynamic in Migraine Patients|
|Actual Study Start Date :||May 24, 2017|
|Actual Primary Completion Date :||November 30, 2017|
|Actual Study Completion Date :||November 30, 2017|
|Active Comparator: Levcromakalim||
To investigate the role of Levcromakalim on cerebral hemodynamic in migraine patients
|Placebo Comparator: Saline||
To investigate the role of levcromakalim compared with saline cerebral hemodynamic in migraine patients.
- Cerebral hemodynamic [ Time Frame: Before (-10 min) and after infusion (+2 hours) of levcromakalim compared with before and after infusion of saline ]Change on Media cerebri arterie.
- Headache [ Time Frame: Before (-10 min) and after infusion (+12 hours) of levcromakalim compared with before and after infusion of saline ]Occurrence of headache.
- Migraine attack [ Time Frame: Before (-10 min) and after infusion (+12 hours) of levcromakalim compared with before and after infusion of saline ]Occurrence
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03228355
|Danish headache center|
|Copenhagen, Glostrup, Denmark, 2600|
|Study Director:||Messoud Ashina, Professor||DHC|