Can Cognitive-bias Modification Training During Inpatient Alcohol Detoxification Reduce Relapse Rates Post-discharge?
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|ClinicalTrials.gov Identifier: NCT02634476|
Recruitment Status : Completed
First Posted : December 18, 2015
Last Update Posted : October 25, 2016
|Condition or disease||Intervention/treatment||Phase|
|Alcohol Dependence||Behavioral: Alcohol approach/avoidance task Behavioral: Sham approach/avoidance task||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||83 participants|
|Intervention Model:||Parallel Assignment|
|Official Title:||Can Cognitive-bias Modification Training During Inpatient Alcohol Detoxification Reduce Relapse Rates Post-discharge?|
|Study Start Date :||June 2014|
|Actual Primary Completion Date :||February 2016|
|Actual Study Completion Date :||February 2016|
Experimental: cognitive bias modification training
Participants complete four sessions of the alcohol approach/avoidance task.
Behavioral: Alcohol approach/avoidance task
The approach-bias modification is a computerised alcohol approach/avoidance task (alcohol-AAT) in which participants are instructed to respond with an approach movement (pulling a joystick) to pictures in landscape orientation and an avoidance movement (pushing a joystick) to pictures in portrait orientation. The size of the image is increased and decreased by pulling and pushing the joystick respectively, generating a sensation of approach or avoidance. Pictures include images of 20 alcoholic and 20 non-alcoholic drinks presented in a fixed orientation such that participants are in effect instructed to respond to pictures of alcohol by making an avoidance movement (pushing the joystick) and to pictures of non-alcoholic soft drinks by making an approach movement (pulling the joystick).
Sham Comparator: sham training
Participants complete four sessions of the sham approach/avoidance task.
Behavioral: Sham approach/avoidance task
The computerised training for the sham condition is the same as for the experimental condition, except that in the sham approach/avoidance task, both landscape and portrait pictures all contain neutral (non-alcohol related).
- Alcohol abstinence [ Time Frame: 2-week follow-up ]We will assess whether the participant has consumed alcohol at any time between exiting the detoxification facility and completing the 2-week follow-up questionnaires.
- Days until relapse [ Time Frame: 2-week follow-up ]In those who drink before the 2-week follow-up, we will assess the number of days between discharge from detoxification and their first drink of alcohol.
- Number of heavy drinking days [ Time Frame: 2-week follow-up ]We will assess the number of days, in the 14 days prior to the 2-week follow-up, on which the participant consumed at least 5 standard drinks of alcohol.
- Alcohol craving [ Time Frame: Immediately after the 4th training session (days 6 or 7 following admission) ]We will assess craving for alcohol following the final session with both a visual analogue scale and the Alcohol Craving Questionnaire (Short Form - Revised).
- Alcohol craving [ Time Frame: 2-week follow-up ]We will assess craving for alcohol following the final session with the Alcohol Craving Questionnaire (Short Form - Revised).
- Abstinence at 3-months [ Time Frame: 3-month follow-up ]We will assess whether the participant has consumed alcohol at any time during the 30 days prior to the 3-month follow-up.
- Decision-making [ Time Frame: Immediately after the 4th training session (days 6 or 7 following admission) ]The Iowa Gambling Task will be administered following the final training session.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02634476
|Box Hill, Victoria, Australia, 3128|
|Principal Investigator:||Victoria Manning, PhD||Senior Research Fellow|