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Relaxation Music to Lower Heart Rate Prior to Cardiac CT

This study has been completed.
Information provided by (Responsible Party):
University Health Network, Toronto Identifier:
First received: December 11, 2013
Last updated: December 5, 2014
Last verified: December 2013
To acquire low radiation dose and good quality cardiac CT images requires scanning at low heart rates which is usually done with beta-blockers. However, in some patients beta-blockers have little effect. This is thought to be due to a different mechanism of action which continues to maintain the heart rate despite administration of beta-blockers. This study aims to look at the effect of music or relaxation tracks to reduce patient heart rate as anxiety is thought to play a role in maintaining high heart rates. This study will randomise patients into a normal standard of care group compared to a normal standard of care group with music/ relaxation track and compare heart rate, radiation dose, image quality, amount of beta-blocker used and patient experience via a State-Trait Anxiety Inventory (STAI) questionnaire.

Condition Intervention
Coronary Artery Disease and Cardiac Anatomy
Patients Undergoing Coronary CT Angiogram
Patients Undergoing CT Pulmonary Vein Angiogram
Patients Undergoing CT Calcium Score
Other: Relaxation Music

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single Blind (Outcomes Assessor)
Official Title: Relaxation Music to Lower Heart Rate Prior to Cardiac CT

Further study details as provided by University Health Network, Toronto:

Primary Outcome Measures:
  • Change in Heart Rate [ Time Frame: Same day as CT scan ]
    Unit of measure - beats per minute

Secondary Outcome Measures:
  • Radiation Dose [ Time Frame: Same day as CT scan ]
    Unit of measure - millisieverts

  • Image Quality [ Time Frame: Same day as CT scan ]
    Measurement tool - Likert Scale. Review of images by two highly experienced cardiac radiologists

  • IV metoprolol dose [ Time Frame: Same day as CT scan ]
    Unit of measurement - milligrams

  • Patient Satisfaction [ Time Frame: Same day as CT scan ]
    Measurement tool - Modified state-trait anxiety inventory (STAI) questionnaire

Enrollment: 197
Study Start Date: December 2013
Study Completion Date: November 2014
Primary Completion Date: May 2014 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: Music Group plus normal standard of care
Patients will listen to music prior and during the scan
Other: Relaxation Music
No Intervention: Control Group - Normal standard of care


Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Age: 18 years and above
  • All patients coming in for non-contrast enhanced calcium score CT, pulmonary vein angiogram, or coronary CT Angiogram

Exclusion Criteria:

  • Deaf
  • CT for Transcatheter aortic valve implantation (TAVI) or congenital heart disease patients
  • Poor english literacy
  • Pacemaker
  • Post CABG
  • Post heart transplant
  Contacts and Locations
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Please refer to this study by its identifier: NCT02069405

Canada, Ontario
University Health Network, Toronto General Hospital
Toronto, Ontario, Canada, m5g2c4
Sponsors and Collaborators
University Health Network, Toronto
Principal Investigator: Elsie Nguyen, MD University Health Network, Joint Department of Medical Imaging
Study Chair: Ming-Yen Ng, BMBS University Health Network, Joint Department of Medical Imaging
  More Information

Responsible Party: University Health Network, Toronto Identifier: NCT02069405     History of Changes
Other Study ID Numbers: 13-6798-AE
Study First Received: December 11, 2013
Last Updated: December 5, 2014

Additional relevant MeSH terms:
Coronary Artery Disease
Myocardial Ischemia
Coronary Disease
Heart Diseases
Cardiovascular Diseases
Arterial Occlusive Diseases
Vascular Diseases processed this record on May 23, 2017