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ClinicalTrials.gov Identifier: NCT02033928
Recruitment Status :
First Posted : January 13, 2014
Last Update Posted : February 28, 2018
Ohio State University Comprehensive Cancer Center
Information provided by (Responsible Party):
Ashley Rosko, Ohio State University Comprehensive Cancer Center
The purpose of this research study is to describe a patients' fitness before and after treatment (whether that treatment be chemotherapy or a transplant). Fitness is a way of measuring a patient's current quality of health. With surveys, questionnaires and blood tests, we hope to create a tool that will give a good picture of patients' ability to tolerate treatment. In the future, we hope to devise the best treatment for a patient based on their "fitness".
Change in Comprehensive Frailty Assessment [ Time Frame: up to 14 months ]
Responses to the Comprehensive Frailty Assessment will be assessed before and after treatment and changes will be evaluated. In transplant patients, this will be measured one year post transplant and in the non-transplant arm, this will be assessed after the second cycle of treatment.
Secondary Outcome Measures :
Time to progression [ Time Frame: date of enrollment to date of documented clinical progression up to two years post-enrollment ]
We will assess time to progression for multiple myeloma patients and the relationships of those outcomes to patients' functional, cognitive and psychosocial health.
Other Outcome Measures:
Overall survival [ Time Frame: enrollment to date of death up to two years post-enrollment ]
We will assess overall survival and the relationship of those measures to patients' functional, cognitive and psychosocial health.
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Layout table for eligibility information
Ages Eligible for Study:
18 Years and older (Adult, Older Adult)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
Patients at The Ohio State University with a plamsa cell dyscrasia and/or any patient receiving a blood or marrow transplant at Ohio State will be considered for this study.
patients with a plasma cell dyscrasia AND/OR any patient receiving a stem cell transplant for a hematologic malignancy at The Ohio State University
at least 18 years of age
- Any medical or psychiatric condition that would make it difficult for the patient to comply with study procedures.