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ClinicalTrials.gov Identifier: NCT01917955
Recruitment Status :
First Posted : August 7, 2013
Last Update Posted : November 8, 2016
Charite University, Berlin, Germany
Center for Stroke Research Berlin
Cardiology and Angiology, Elisabeth Hospital, Essen, Germany
Information provided by (Responsible Party):
Karl Georg Haeusler, Charite University, Berlin, Germany
The purpose of this prospective single-center trial is to compare the safety and diagnostic value of contrast medium-enhanced cardiac magnetic resonance imaging and transesophageal echocardiography in patients with acute ischemic stroke.
Condition or disease
Primary safety objective: Contrast medium-enhanced cardiac magnetic resonance imaging is safe in patients with acute ischemic stroke. Primary outcome: The diagnostic value of contrast medium-enhanced cardiac magnetic resonance imaging is comparable to transesophageal echocardiography in patients with acute ischemic stroke.
Sensitivity and specificity of contrast medium-enhanced cardiac magnetic resonance imaging to detect echocardiography-proven cardiac sources of embolism in patients with acute ischemic stroke. [ Time Frame: < 1 week after ischemic stroke ]
Secondary Outcome Measures :
Rate of unrecognised myocardial infarction detected by late gadolinium-enhanced cardiac MRI in patients with acute ischemic stroke. [ Time Frame: < 1 week after ischemic stroke ]
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Ages Eligible for Study:
18 Years and older (Adult, Senior)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
Overall, 103 patients with acute ischemic stroke detected by brain magnetic resonance imaging will be enrolled.
Patients with acute ischemic stroke detected by brain magnetic resonance imaging.
Known atrial fibrillation or cardiac source of embolism
Acute infection or chronic inflammation
Severe arteriosclerosis or stenosis of brain-supplying arteries
Contraindications for magnetic resonance imaging or transesophageal echocardiography.