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Effect of Pumpkin Seed Oil on Hair Growth in Men With Androgenetic Alopecia

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
 
ClinicalTrials.gov Identifier: NCT01852487
Recruitment Status : Completed
First Posted : May 13, 2013
Last Update Posted : May 13, 2013
Sponsor:
Information provided by (Responsible Party):
Young Hye Cho, Pusan National University Yangsan Hospital

Study Description
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Brief Summary:

Androgenic alopecia is the most common cause of hair loss in men. Finasteride and minoxidil are available in treatment of androgenetic alopecia, although the former causes decreased libido or ejaculate volume, erectile dysfunction, the latter causes scaling, itching of the scalp. Recently, Pulpkin Seed Oil shows some improved clinical efficacy on scalp hair growth in men with androgenetic alopecia, but there is no evidence to support this.

The investigators conducted a randomized, double-blind, placebo-controlled efficacy and tolerability trial of Pumpkin seed oil (400mg/day)therapy in male patients with androgenetic alopecia.


Condition or disease Intervention/treatment Phase
Androgenic Alopecia Dietary Supplement: 400mg /day during 6 months Not Applicable

Study Design
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Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 80 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
Primary Purpose: Treatment
Study Start Date : February 2012
Actual Primary Completion Date : December 2012
Actual Study Completion Date : December 2012

Resource links provided by the National Library of Medicine


Arms and Interventions
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Arm Intervention/treatment
Active Comparator: Pumpkin Seed Oil
400mg/ day during 6 months
 Dietary Supplement: 400mg /day during 6 months
Placebo Comparator: sweet potato starch
400mg/day during 6months


Outcome Measures
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Primary Outcome Measures :
  1. investigator assessment score using photographs of scalp hair [ Time Frame: at weeks 12 and 24 ]

Secondary Outcome Measures :
  1. patient self-assessment scores [ Time Frame: at weeks 12 and 24 ]

Other Outcome Measures:
  1. hair analysis using phototrichogram [ Time Frame: at weeks 12 and 24 ]

Eligibility Criteria
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Ages Eligible for Study:   18 Years to 65 Years   (Adult, Older Adult)
Sexes Eligible for Study:   Male
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • 18 to 65 years of age
  • Androgenetic alopecia of Norwood-Hamilton scale grade II-V

Exclusion Criteria:

  • Severe medical problems including renal problems, prostate diseases, diabetes mellitus o
  • Patients who took any medicine which can affect the hair growth in recent 3 months.
Contacts and Locations
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Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01852487


Locations
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Korea, Republic of
Pusan National University Yangsan Hospital
Yangsan, Gyeongsangnam-do, Korea, Republic of, 626-770
Sponsors and Collaborators
Dream Plus
More Information
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Responsible Party: Young Hye Cho, Professor, Pusan National University Yangsan Hospital
ClinicalTrials.gov Identifier: NCT01852487    
Other Study ID Numbers: Pumpkin0912
First Posted: May 13, 2013    Key Record Dates
Last Update Posted: May 13, 2013
Last Verified: May 2013
Keywords provided by Young Hye Cho, Pusan National University Yangsan Hospital:
Pumpkin seed oil
Hair growth
Men
Additional relevant MeSH terms:
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Alopecia
Alopecia Areata
Hypotrichosis
 Hair Diseases
Skin Diseases
Pathological Conditions, Anatomical