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The Determination of Important Mechanical Patterns of Left Ventricular Efficiency-MV02 Study (DIMPLE)

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ClinicalTrials.gov Identifier: NCT01807819
Recruitment Status : Recruiting
First Posted : March 8, 2013
Last Update Posted : January 26, 2018
Sponsor:
Information provided by (Responsible Party):
University of Florida

Brief Summary:
The purpose of this study is to determine if analysis of heart ultrasound images with new software programs will provide better understanding as to the specific heart problems that lead to symptoms of heart failure.

Condition or disease Intervention/treatment
Heart Failure Other: Heart Failure

  Show Detailed Description

Study Type : Observational
Estimated Enrollment : 150 participants
Observational Model: Cohort
Time Perspective: Prospective
Official Title: The Determination of Important Mechanical Patterns of Left Ventricular Efficiency-MV02 Study
Actual Study Start Date : August 2013
Estimated Primary Completion Date : February 2019
Estimated Study Completion Date : February 2019

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Heart Failure
U.S. FDA Resources

Group/Cohort Intervention/treatment
Heart Failure
Patients will undergo echocardiogram and exercise testing. Two year phone follow-up.
Other: Heart Failure
Patients will undergo echocardiogram and exercise testing. Two year phone follow-up.



Primary Outcome Measures :
  1. Correlation of myocardial strain with maximal oxygen consumption [ Time Frame: Baseline ]

Secondary Outcome Measures :
  1. Cardiovascular Hospitalization [ Time Frame: Baseline to 2 years ]
  2. Cardiovascular Death [ Time Frame: Baseline to 2 years ]


Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Patients 18 years of age or older who are referred to our adult cardiovascular heart failure clinics for evaluation of heart failure or LV dysfunction
Criteria

Inclusion Criteria:

  • Patients 18 years of age or older who are referred to our adult cardiovascular heart failure clinics for evaluation of heart failure or LV dysfunction.

Exclusion Criteria:

  • Patients with contraindications to exercise testing:(myocardial infarction within 2 days, unstable angina, uncontrolled cardiac arrhythmias, severe aortic stenosis, uncontrolled symptomatic heart failure, recent pulmonary embolism, recent myocarditis, history of aortic dissection, untreated ischemic CAD, blood pressure > 200/110, history of untreated tachy- or brady arrhythmia, hypertrophic cardiomyopathy, or inability to perform exercise because of physical or mental impairment) will be excluded from the study.

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01807819


Contacts
Contact: John W Petersen, MD 352-273-9076

Locations
United States, Florida
University of Florida, Shands Cardiovascular Clinic Recruiting
Gainesville, Florida, United States, 32610
Contact: John W Petersen, MD    352-273-9076      
Principal Investigator: John W Petersen, MD         
Sponsors and Collaborators
University of Florida
Investigators
Principal Investigator: John W Petersen, MD University of Florida

Responsible Party: University of Florida
ClinicalTrials.gov Identifier: NCT01807819     History of Changes
Other Study ID Numbers: IRB201602538
27-2013 ( Other Identifier: uf legacy )
First Posted: March 8, 2013    Key Record Dates
Last Update Posted: January 26, 2018
Last Verified: January 2018

Keywords provided by University of Florida:
Heart Failure
Myocardial Strain
Functional Capacity

Additional relevant MeSH terms:
Heart Failure
Heart Diseases
Cardiovascular Diseases