Prevalence and Incidence of Central Airway Obstruction in Advanced Lung Cancer
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|ClinicalTrials.gov Identifier: NCT01799395|
Recruitment Status : Terminated (Staff constraints made it impossibile to enroll consecutive patients, making the sample not representative of the true cancer population)
First Posted : February 26, 2013
Last Update Posted : September 12, 2017
Lung cancer may cause central airway obstruction through several different mechanisms (invasion by the primary tumor, invasion by metastatic lymph nodes, airway metastasis).
The aim of the present study is to determine the prevalence at the time of diagnosis, the incidence at 1 year from the diagnosis, and the predictors of central airway obstruction associated with advanced lung cancer.
|Condition or disease|
|Study Type :||Observational|
|Actual Enrollment :||45 participants|
|Official Title:||Prevalence, Incidence and Predictors of Central Airway Obstruction in Patients With Advanced Lung Cancer|
|Study Start Date :||February 2013|
|Actual Primary Completion Date :||March 2015|
|Actual Study Completion Date :||March 2015|
All patients with advanced lung cancer candidate for chemotherapy or chemotherapy + radiation therapy will be enrolled and followed-up for 1 year clinically and radiologically (Chest CT) to verify whether or not central airway obstruction is present at the time of diagnosis or occurs in the year following diagnosis (or in the life span from diagnosis and death in patients who die before 1 year of diagnosis). Furthermore, predictor variables possibly associated with central airway obstruction will be studied.
- Incidence of central airway obstruction [ Time Frame: 12 months ]The incidence will be measured over a 12 month period after diagnosis (or over the life span from diagnosis to death in patients who die before 1 year from the diagnosis)
- Predictor variables associated with the presence/occurrence of central airway obstruction [ Time Frame: 12 months ]
- Prevalence of central airway obstruction [ Time Frame: 1 day ]The prevalence of central airway obstruction will be evaluated at the time of diagnosis
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01799395
|Bentivoglio, Emilia Romagna, Italy, 40010|
|Bologna, Emilia Romagna, Italy, 40100|
|Bologna, Emilia Romagna, Italy, 4013|
|Budrio, Emilia Romagna, Italy, 40054|
|SS Salvatore Hospital|
|San Giovanni in Persiceto, Emilia Romagna, Italy, 40017|
|Principal Investigator:||Rocco Trisolini, M.D.||Maggiore Bellaria Hospital, Bologna, Italy|