Efficacy Study of Intranasal Insulin to Treat Tobacco Abstinence Syndrome
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Ages Eligible for Study:
18 Years to 65 Years (Adult)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
smokers (>10 cig/day) for the past 1 year
normosmic olfactory function
previous/current use of insulin
current Diagnostic and Statistical Manual-IV-Revised (DSM-IV-R) Axis I disorder
current pregnancy (or lactation)
lifetime history of endocrine disease
excessive alcohol use (>25 standard units of alcohol/week)
current use of illicit drugs
current use of a smoking cessation aid (NRT, Chantix or Wellbutrin), or a psychotropic agent
local infections, inflammation, structural abnormalities, or other nasal pathology
current use of any medications administered intranasally, including intranasal steroids