Comparison of the Evaluation of CAD by CT AngioScan and Coronary Angiogram (CTAS-MCAS)

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT01779986
Recruitment Status : Unknown
Verified January 2013 by Université de Sherbrooke.
Recruitment status was:  Recruiting
First Posted : January 30, 2013
Last Update Posted : January 30, 2013
Information provided by (Responsible Party):
Université de Sherbrooke

Brief Summary:
The use of CT Coronary Angioscan (CT-AS) is gaining popularity, but its exact value as evaluation of CAD requires confirmation. We intend to compare the results of CT-AS and convention coronary angiogram results in patients who are scheduled for an ascending aorta aneurysm reparation surgery. These examens are standard of care before this surgery, so there is no additional danger or disadvantage for the patient. We hope to confirm that CT-AS is a reliable screening test for CAD in patient undergoing heart surgery for other reason than CAD.

Condition or disease
Coronary Artery Disease

Study Type : Observational
Estimated Enrollment : 100 participants
Observational Model: Cohort
Time Perspective: Prospective
Official Title: Comparison of the Evaluation of CAD by CT AngioScan and Coronary Angiogram in Patient as Part of Preoperative Evaluation in Ascending Aorta Replacement Surgery Patients.
Study Start Date : January 2013
Estimated Primary Completion Date : February 2015
Estimated Study Completion Date : February 2015

Primary Outcome Measures :
  1. Presence of CAD [ Time Frame: less than 6 monthes between two tests ]
    The CAD seen on CT-AS as compared to the results of the gold-standard test of coronary angiogram.

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Ages Eligible for Study:   18 Years to 89 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Patients with ascending aorta aneurysm undergoing preoperative evaluation of CAD by CT-Angioscan and Coronary angiogramm before surgical reparation.

Inclusion Criteria:

  • Ascending aorta aneurysm waiting for surgical correction
  • Willing to participate
  • Needing a Coronary angiogram and a CT-AS for medical reasons

Exclusion Criteria:

  • Refuse to participate
  • Allergy to contrast material
  • Incomplete results or having one of the test done in another hospital
  • Arrythmia
  • More than 6 months between the two exams

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT01779986

Canada, Quebec
CHUS Fleurimont Recruiting
Sherbrooke, Quebec, Canada, J1H 5N4
Contact: Paul Farand, M.Sc    819-346-1110   
Principal Investigator: Gérald Gahide, MD         
Sub-Investigator: Paul Farand, MD, MSc         
Sub-Investigator: Tamas Z Fulop, MD         
Sub-Investigator: Francis Rivest, MD         
Sponsors and Collaborators
Université de Sherbrooke
Principal Investigator: Gerald Gahide, MD PHD Université de Sherbrooke

Responsible Party: Université de Sherbrooke Identifier: NCT01779986     History of Changes
Other Study ID Numbers: CTAS-MCAS UdeS 12-073
First Posted: January 30, 2013    Key Record Dates
Last Update Posted: January 30, 2013
Last Verified: January 2013

Additional relevant MeSH terms:
Coronary Artery Disease
Myocardial Ischemia
Coronary Disease
Heart Diseases
Cardiovascular Diseases
Arterial Occlusive Diseases
Vascular Diseases