Brief Multifamily Psychoeducation for Families of Patients With Chronic Major Depression
The purpose of this study is to examine the effectiveness of brief multifamily psychoeducation to relieve the psychological distress of families of patients with chronic major depression and to improve their family functioning.
Major Depressive Disorder
Behavioral: Family psychoeducation
|Study Design:||Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment
|Official Title:||Brief Multifamily Psychoeducation for Families of Patients With Chronic Major Depression: A Randomized Controlled Trial|
- The change of total score of K6 of family members [ Time Frame: The base line, 8, 16 and 32 ] [ Designated as safety issue: No ]The K6 questionnaire is a six-item self-report questionnaire that was developed to screen for DSM-IV depressive and anxiety disorder.
- The change of total score of Family Attitude Scale(FAS) of family members [ Time Frame: The base line, 8, 16 and 32 ] [ Designated as safety issue: No ]The Family Attitude Scale(FAS) is a 30-item self report inventory and measures families' Expressed Emotion(EE).
|Study Start Date:||October 2012|
|Estimated Study Completion Date:||June 2016|
|Estimated Primary Completion Date:||December 2015 (Final data collection date for primary outcome measure)|
Active Comparator: Family psychoeducation plus TAU
Family psychoeducational therapy in addition to treatment as usual for the patients.
Behavioral: Family psychoeducation
Family psychoeducational therapy every two weeks for six weeks in addition to treatment as usual administered by physicians
Placebo Comparator: Treatment as usual(TAU)
Treatment as usual administered by physician and counseling administered by nurse.
Major depressive disorder (MDD) is a long-lasting illness with significant effects on the patient's family, social life, and work life. Treatment failure results in a low recovery rate and frequent relapses.
Relatives of patients with MDD are fraught with heavy psychosocial burden and show increased rates of depression and anxiety. Among relatives of patients with MDD, the patient's behavior and mood disturbance and relative's emotional distress were associated with the relatives' burden.
Family psychoeducation is recognized as part of the optimal treatment for patients with psychotic disorder. This intervention has been shown to reduce the rates of relapse and hospitalization among individuals with psychotic disorders and is recognized as an evidenced-based treatment for psychotic disorder. Several randomized controlled trials have found that family psychoeducation is effective in enhancing the course of bipolar disorder. However, there are few studies on psychoeducation of families of patients with MDD.
The purpose of this study is to examine the effectiveness of brief multifamily psychoeducation to relieve the psychological distress of families of patients with chronic major depression and to improve their family functioning, in a randomized controlled trial.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01734291
|Contact: Fujika Katsuki, Dremail@example.com|
|Nagoya, Aichi, Japan, 467-8601|
|Contact: Fujika Katsuki, Dr +81-52-853-8048 firstname.lastname@example.org|
|Contact: Norio Watanabe, Dr email@example.com|
|Principal Investigator:||Fujika Katsuki, Dr||Nagoya City University, School of Nursing|