Brain Imaging Plus Urodynamics to Investigate the Brain's Control of the Bladder (NIRS/fBFB)
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government.
Read our disclaimer for details.
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.
Ages Eligible for Study:
60 Years and older (Adult, Senior)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
women over 60 years
ambulatory women over age 60, who are incontinent at least five times weekly for 3 months despite correction of potentially reversible causes.
urinary incontinence (urge or predominantly urge) by clinical criteria.
able to accurately complete a voiding diary, to perform a 24-hour pad test under direction.
significant mental impairment [mini mental status exam (MMSE) ≤ 20)
history of bladder cancer
spinal cord lesions
artificial sphincter implant
expected to have changes in medications/doses during the trial
Patients with factors that could cause transient UI [e.g., current urinary tract infection (UTI), acute confusion] will be treated in concert with the subject's primary care provider and considered for enrollment if their UI persists.
conditions that require endocarditis prophylaxis (such as heart valve problems or bacterial endocarditis)