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Lower Extremity Muscle and Function in the Elderly: Study 2

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT01614392
First Posted: June 7, 2012
Last Update Posted: June 7, 2012
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by (Responsible Party):
Roger A Fielding, Tufts University
  Purpose
This research study is looking to compare the effects of two uniquely different power training interventions (high force, lower velocity versus low force, high velocity) on changes in mobility status among older individuals at risk for mobility disability.

Condition Intervention
Mobility Limitation Behavioral: Lower Extremity high velocity low force Power Training

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single (Investigator)
Primary Purpose: Treatment
Official Title: Lower Extremity Muscle and Function in the Elderly: Study 2

Further study details as provided by Roger A Fielding, Tufts University:

Primary Outcome Measures:
  • Peak lower extremity velocity [ Time Frame: Change from Baseline to Week 4, change from baseline to Week 16 ]

Secondary Outcome Measures:
  • Muscle Strength [ Time Frame: Change from Baseline to week 4, change from baseline to Week 16 ]

Enrollment: 52
Study Start Date: September 2009
Study Completion Date: October 2011
Primary Completion Date: October 2011 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: Lower Extremity Power Training Behavioral: Lower Extremity high velocity low force Power Training
Lower Extremity high velocity, low force Power Training
Other Name: Lower Extremity low velocity, high force power training
Experimental: Lower Extremity power training Behavioral: Lower Extremity high velocity low force Power Training
Lower Extremity high velocity, low force Power Training
Other Name: Lower Extremity low velocity, high force power training

  Eligibility

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Ages Eligible for Study:   70 Years to 85 Years   (Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Male and Female 70-85 yrs
  • Community dwelling
  • Short Performance Battery Score >9
  • BMI range 19-32 kg/m2
  • Willingness to be randomized and come the laboratory for 20 weeks.

Exclusion Criteria:

  • Acute or Terminal Illness
  • MI in previous 6 months, symptomatic coronary artery disease or congestive heart failure.
  • Upper or Lower extremity fracture in previous 6 months
  • Uncontrolled hypertension (150/90mmHg)
  • Neuromuscular diseases and drugs that affect neuromuscular function
  • Hormone replacement therapy
  • Participation in any regular endurance or resistance training exercise during previous 3 months
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01614392


Locations
United States, Massachusetts
Jean Mayer USDA Human Nutrition Research Center on Aging
Boston, Massachusetts, United States, 02111
Sponsors and Collaborators
Tufts University
Investigators
Principal Investigator: Roger A Fieilding, Ph D. Jean Mayer USDA Human Nutrition Research Center on Aging
  More Information

Responsible Party: Roger A Fielding, Director and Senior Scientist, Professor of Nutrition, Jean Mayer USDA Human Nutrition Research Center on Aging., Tufts University
ClinicalTrials.gov Identifier: NCT01614392     History of Changes
Other Study ID Numbers: AG-18844
First Submitted: September 28, 2009
First Posted: June 7, 2012
Last Update Posted: June 7, 2012
Last Verified: June 2012

Keywords provided by Roger A Fielding, Tufts University:
Resistance Exercise
Physical Activity
Mobility disability
Physical function
Muscle Strength
Older Adults
Mobility-Limited
Peak power and strength

Additional relevant MeSH terms:
Mobility Limitation
Signs and Symptoms


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