Behavior During Experimentally Induced Pain
|Study Design:||Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Prevention
|Official Title:||Behavior During Experimentally Induced Pain|
- Frequency of behavioral signs [ Time Frame: during pain tests (average 1 hour) ] [ Designated as safety issue: No ]number of corporal mobility, facial expression and sound indicators
|Study Start Date:||April 2012|
|Study Completion Date:||December 2013|
|Primary Completion Date:||December 2013 (Final data collection date for primary outcome measure)|
No Intervention: diagnosis
diagnosis according to the DSM-IV-TR : major depression and schizophrenia, or control.
Other: pain tests
pain induction with pressure application or ischemia on the arm
The objective is to search for behavioral non verbal indicators of pain during experimentally induced pain (pressure application, ischemia induction).
Included subjects are subjected to experimental pain tests : pressure application (160 kPa) with an algometer to determine the pain with Visual Analogic Scale (VAS), and ischemia induction to determine the time needed to feel pain with an intensity equivalent to 3 with the VAS.
Subjects are filmed during experimentation to identify the corporal mobility signs, facial expression signs and sonorous signs associated to pain stimulation.
Neurophysiological measures complete these observations : surface electromyogram, heart rate measure, blood pressure.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01594528
|Centre Hospitalier Esquirol|
|Limoges, France, 87025|
|Principal Investigator:||Dominique Malauzat, MD||Centre Hospitalier Esquirol|