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Skin Blood Flow in Patients With Type 1 Diabetes Mellitus Compared to Normal Controls

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT01592539
First Posted: May 7, 2012
Last Update Posted: February 26, 2015
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by (Responsible Party):
Laura Armas, Creighton University
  Purpose
The effects of high serum glucose on bone could be direct or could be indirect through its effects on the microvasculature. Previous studies by Rendell et al and Brugler et al have found significant differences in skin blood flow between diabetics and control. The investigators are proposing that blood flow measurements of the skin may be correlated with bone remodeling rates in iliac bone biopsies.

Condition
Type 1 Diabetes, Bone

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Cross-Sectional
Official Title: Skin Blood Flow in Patients With Type 1 Diabetes Mellitus Compared to Normal Controls

Resource links provided by NLM:


Further study details as provided by Laura Armas, Creighton University:

Enrollment: 78
Study Start Date: May 2012
Study Completion Date: August 2013
Primary Completion Date: August 2013 (Final data collection date for primary outcome measure)
Groups/Cohorts
Case
Patients with Type 1 Diabetes Mellitus
Control
Age and sex matched healthy controls.

  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   19 Years to 50 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
Patients with Type 1 DM
Criteria

Inclusion Criteria:

  • Must have completed a previous study.
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01592539


Locations
United States, Nebraska
Creighton University
Omaha, Nebraska, United States, 68131
Sponsors and Collaborators
Creighton University
Investigators
Principal Investigator: Laura AG Armas, MD Creighton University
  More Information

Responsible Party: Laura Armas, Assistant Professor, Creighton University
ClinicalTrials.gov Identifier: NCT01592539     History of Changes
Other Study ID Numbers: Creighton11
First Submitted: May 3, 2012
First Posted: May 7, 2012
Last Update Posted: February 26, 2015
Last Verified: February 2015

Keywords provided by Laura Armas, Creighton University:
Type 1 Diabetes
Bone

Additional relevant MeSH terms:
Diabetes Mellitus
Diabetes Mellitus, Type 1
Glucose Metabolism Disorders
Metabolic Diseases
Endocrine System Diseases
Autoimmune Diseases
Immune System Diseases