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Skin Blood Flow in Patients With Type 1 Diabetes Mellitus Compared to Normal Controls

This study has been completed.
Information provided by (Responsible Party):
Laura Armas, Creighton University Identifier:
First received: May 3, 2012
Last updated: February 25, 2015
Last verified: February 2015
The effects of high serum glucose on bone could be direct or could be indirect through its effects on the microvasculature. Previous studies by Rendell et al and Brugler et al have found significant differences in skin blood flow between diabetics and control. The investigators are proposing that blood flow measurements of the skin may be correlated with bone remodeling rates in iliac bone biopsies.

Type 1 Diabetes,

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Cross-Sectional
Official Title: Skin Blood Flow in Patients With Type 1 Diabetes Mellitus Compared to Normal Controls

Resource links provided by NLM:

Further study details as provided by Creighton University:

Enrollment: 78
Study Start Date: May 2012
Study Completion Date: August 2013
Primary Completion Date: August 2013 (Final data collection date for primary outcome measure)
Patients with Type 1 Diabetes Mellitus
Age and sex matched healthy controls.


Ages Eligible for Study:   19 Years to 50 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
Patients with Type 1 DM

Inclusion Criteria:

  • Must have completed a previous study.
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Please refer to this study by its identifier: NCT01592539

United States, Nebraska
Creighton University
Omaha, Nebraska, United States, 68131
Sponsors and Collaborators
Creighton University
Principal Investigator: Laura AG Armas, MD Creighton University
  More Information

Responsible Party: Laura Armas, Assistant Professor, Creighton University Identifier: NCT01592539     History of Changes
Other Study ID Numbers: Creighton11
Study First Received: May 3, 2012
Last Updated: February 25, 2015

Keywords provided by Creighton University:
Type 1 Diabetes

Additional relevant MeSH terms:
Diabetes Mellitus
Diabetes Mellitus, Type 1
Glucose Metabolism Disorders
Metabolic Diseases
Endocrine System Diseases
Autoimmune Diseases
Immune System Diseases processed this record on May 24, 2017