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LiDCO Monitor Study

This study has been completed.
Information provided by (Responsible Party):
Joseph D. Tobias, Nationwide Children's Hospital Identifier:
First received: March 26, 2012
Last updated: March 16, 2016
Last verified: March 2016
This is a study to validate the utility and accuracy of the non-invasive device (LiDCOrapid monitor) during a period of phlebotomy and graded blood loss in patients who are having cardiac surgery.

Condition Intervention
Cardiac Surgery
Device: LiDCO rapid monitor

Study Type: Interventional
Study Design: Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Diagnostic
Official Title: Use of the LiDCORapid Monitor in Patients During Graded Phlebotomy and the Removal of Autologous Blood

Further study details as provided by Nationwide Children's Hospital:

Primary Outcome Measures:
  • Difference in Pulse Pressure Variability From Baseline to Post-ANH [ Time Frame: 1 Day ]
    The difference in pulse pressure variability during a period of phlebotomy and graded blood loss, measured before phlebotomy or acute normovolemic hemodilution (ANH) and immediately after.

Secondary Outcome Measures:
  • Difference in Stroke Volume Variability From Baseline to Post ANH. [ Time Frame: 1 Day ]
    The difference in stroke volume variability during a period of phlebotomy and graded blood loss, measured before phlebotomy or acute normovolemic hemodilution (ANH) and immediately after.

Enrollment: 30
Study Start Date: March 2012
Study Completion Date: March 2015
Primary Completion Date: December 2014 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: LiDCO rapid monitor Device: LiDCO rapid monitor
Technology which provides a continuous means of monitoring various hemodynamic parameters including cardiac output and pulse pressure variability.


Ages Eligible for Study:   Child, Adult, Senior
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Patients scheduled for intraoperative phlebotomy following anesthetic induction to obtain autologous blood for use following cardiopulmonary bypass and cardiac surgery.
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Please refer to this study by its identifier: NCT01567371

United States, Ohio
Nationwide Children's Hospital
Columbus, Ohio, United States, 43205
Sponsors and Collaborators
Nationwide Children's Hospital
  More Information

Responsible Party: Joseph D. Tobias, Chairman, Dept. of Anesthesiology & Pain Medicine, Nationwide Children's Hospital Identifier: NCT01567371     History of Changes
Other Study ID Numbers: IRB12-00096
Study First Received: March 26, 2012
Results First Received: March 16, 2016
Last Updated: March 16, 2016 processed this record on May 25, 2017