This site became the new on June 19th. Learn more.
Show more Menu IMPORTANT: Listing of a study on this site does not reflect endorsement by the National Institutes of Health. Talk with a trusted healthcare professional before volunteering for a study. Read more... Menu IMPORTANT: Talk with a trusted healthcare professional before volunteering for a study. Read more... Menu
Give us feedback

International Cross-sectional and Longitudinal Assessment on Asthma Control (Liaison) (LIAISON)

This study has been completed.
Information provided by (Responsible Party):
Chiesi Farmaceutici S.p.A. Identifier:
First received: March 29, 2012
Last updated: January 19, 2015
Last verified: January 2015

The study design consists of a cross-sectional survey on the clinical characteristics of patients with asthma and their level of asthma control and current quality of life, and on a prospective evaluation of the rate of switch from the uncontrolled/poorly controlled condition to the status of controlled asthma. Asthma control will be based on the Asthma Control Questionnaire scoring system, that has been fully validated for use in both clinical practice and clinical trials and has strong discriminative properties which means that it can detect small differences between patients with different levels of asthma control and it is very sensitive to within-patient change in asthma control over time.

Quality of life as a reflection of the control of the disease, will also be evaluated by means of the Mini Asthma Quality of Life Questionnaire scoring system.


Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: International Cross-sectional and Longitudinal Assessment on Asthma Control (Liaison)

Further study details as provided by Chiesi Farmaceutici S.p.A.:

Primary Outcome Measures:
  • Asthma Control Questionnaire score [ Time Frame: 3 months ]
  • Mini Asthma Quality of Life Questionnaire score [ Time Frame: 3 months ]

Enrollment: 8111
Study Start Date: May 2012
Study Completion Date: October 2014
Primary Completion Date: October 2013 (Final data collection date for primary outcome measure)
Controlled patients
Asthmatic patients with controlled asthma (according to ACQ score)
Partly controlled/Uncontrolled patients
Patients with partly controlled or uncontrolled asthma (according to ACQ score)


Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
Asthmatic patients (in treatment with the same antiasthmatic therapy for at least 4 weeks) visiting the centre.

Inclusion Criteria:

  • Inclusion criteria:

    1. Written informed consent obtained.
    2. Male or female adult (at least 18 years of age) patients with asthma diagnosed (according to GINA guidelines and confirmed by a chest physician) for at least 6 months.
    3. Patients in treatment with the same antiasthmatic drugs in the last 4 weeks before enrolment.
  • Exclusion criteria:

    1. Patients enrolled in clinical trial in the previous 4 weeks or subjects already admitted in this study.
    2. Patients suffering from conditions and illnesses that might interfere with the study purpose, according to the investigator's evaluation.
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT01567280

Azienda Sanitaria Firenze Piero Palagi
Firenze, Italy, 50125
Sponsors and Collaborators
Chiesi Farmaceutici S.p.A.
  More Information

Publications automatically indexed to this study by Identifier (NCT Number):
Responsible Party: Chiesi Farmaceutici S.p.A. Identifier: NCT01567280     History of Changes
Other Study ID Numbers: DFIDM-1101
Study First Received: March 29, 2012
Last Updated: January 19, 2015

Additional relevant MeSH terms:
Bronchial Diseases
Respiratory Tract Diseases
Lung Diseases, Obstructive
Lung Diseases
Respiratory Hypersensitivity
Hypersensitivity, Immediate
Immune System Diseases processed this record on August 18, 2017