Osteoporosis in Chronic Obstructive Pulmonary Disease (COPD)
Recruitment status was: Recruiting
Patients with chronic obstructive pulmonary disease (COPD) are at increased risk of osteoporosis and fractures. Osteoporosis, however, may be equally as disabling as COPD, and may impair respiratory function even further if the patient experiences vertebral compressions.
In this study, we will survey the prevalence, correlations and effectiveness of intervention of osteoporosis in COPD patients.
|Study Design:||Endpoint Classification: Efficacy Study
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Treatment
|Official Title:||The Prevalence, Correlations and Effectiveness of Intervention of Osteoporosis in COPD Patients|
- exercise tolerance. [ Time Frame: 3 months ] [ Designated as safety issue: Yes ]Exercise tolerance will be measured by six-minutes walking test after trainsing with 3 months mobile-based pulmonary rehabilitation program. Wlaking distences will be the primary outcome measurement.
- Inflammatory cytokine of patients. [ Time Frame: 3 months and 1 year ] [ Designated as safety issue: No ]Inflammatory cytokine of enrolled patients including IL-6、IL-8、TNF-α & CRP before and 3 months, 1 year after moble-based pulomonary rehabilitation program will be measured.
|Study Start Date:||September 2011|
|Estimated Study Completion Date:||December 2014|
|Estimated Primary Completion Date:||December 2014 (Final data collection date for primary outcome measure)|
Experimental: Mobile-based PR program.
Home based mobile PR program for 3 months.
Behavioral: mobile-based PR program.
Patients will be trained and monitored by mobile-based pulmonary rehbailitation program. By mobile, patients could undergo exercise training at home and the information of training parameters will be send to investigator. Investigator could monitor these patients by mobile. Patients will return to visit physian and receive six-minutes walking test to measure outcomes 3 months and 1 year later after mobile-based pulmonary rehabilitation program.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01549028
|Chang Gung Memorial Hospital|
|Taoyuan, Taiwan, 333|
|Principal Investigator:||Shu-Chuan Ho, PhD||Chang Gung Memorial Hospital|