From Acute to Chronic Postoperative Pain in Patients for Elective Cholecystectomy. Immunological Tests
Chronic Pain after Cholecystectomy is a well known problem. One theory is that it is due to persisting inflammation.
The purpose of the study is to measure inflammatory factors in cerebrospinal fluid and blod at patients 12 months after the operation.
DNA-samples are collected to examine genetical factors, important for perception of pain, and the development of chronic pain.
|Study Design:||Observational Model: Case Control
Time Perspective: Prospective
|Official Title:||From Acute to Chronic Postoperative Pain in Patients for Elective Cholecystectomy. Immunological Tests|
- Spinal interleukine levels [ Time Frame: 12 months ]12 months after surgery
- Blood interleukine levels [ Time Frame: 12 Months ]
- spinal enzyme levels [ Time Frame: 12 months ]12 months after surgery
- Blood enzyme levels [ Time Frame: 12 months ]12 months after surgery
Biospecimen Retention: Samples With DNA
|Study Start Date:||November 2011|
|Study Completion Date:||February 2014|
|Primary Completion Date:||February 2014 (Final data collection date for primary outcome measure)|
Patients with unexplained chronic abdominal pain 12 months after elective cholecystectomy
Operated painfree Patients
Painfree patients 12 months after elective cholecystectomy
Nonoperated painfree patients
Painfree patients with no previous abdominal operation
Please refer to this study by its ClinicalTrials.gov identifier: NCT01546480
|Odense University Hospital|
|Odense, Denmark, 5000|
|Vejle, Denmark, 7100|