Correlation of PaCO2 to the Inspired and Expired Oxygen Gradient (O2 Fraction)

This study is ongoing, but not recruiting participants.

Sponsor:

Information provided by (Responsible Party):

Swedish Medical Center

ClinicalTrials.gov Identifier:

NCT01513213

First received: January 5, 2012

Last updated: March 1, 2016

Last verified: March 2016

History of Changes

Purpose

The purpose of this study is to evaluate whether a correlation exists between the partial pressure of carbon dioxide existing within arterial blood and the gradient between inhaled and exhaled fractions of oxygen.

Condition
Neurosurgery


Study Type:	Observational
Study Design:	Observational Model: Case-Only Time Perspective: Cross-Sectional
Official Title:	Correlation of PaCO2 to the Inspired and Expired Oxygen Gradient

Resource links provided by NLM:

MedlinePlus related topics: Oxygen Therapy

U.S. FDA Resources

Further study details as provided by Swedish Medical Center:

Primary Outcome Measures:

Correlate the level of carbon dioxide within arterial blood to inspired and expired oxygen gradient. [ Time Frame: At least 2 hours ] [ Designated as safety issue: No ]
Compare the levels of carbon dioxide found in the patient's blood to the amounts of carbon dioxide and oxygen in the air that the patient inhales and exhales. If a relationship exists between the levels of carbon dioxide in the blood and the levels of carbon dioxide and oxygen inhaled and exhaled by the patient, anesthesiologists will be able to use this relationship to adjust ventilators during anesthesia without having to take blood from an artery.


Estimated Enrollment:	50
Study Start Date:	October 2011
Estimated Study Completion Date:	December 2016
Primary Completion Date:	May 2014 (Final data collection date for primary outcome measure)

Eligibility


Ages Eligible for Study:	18 Years to 65 Years (Adult)
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No
Sampling Method:	Non-Probability Sample

Study Population

Adults age 18 to 65 scheduled for a surgical procedure that will last at least two hours and for whom arterial cannulation and at least two arterial blood gas analyses are planned during the surgery.

Criteria

Inclusion Criteria:

Age 18 to 65.
Scheduled for surgical procedure that will last at least 2 hours.
Arterial cannulation is planned because of either the complexity of the surgery or patient comorbidity.
At least two arterial blood gas analyses are planned during the surgery.

Exclusion Criteria:

No arterial cannulation is necessary or planned for the procedure.

Contacts and Locations

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01513213

Locations


United States, Washington
Swedish Medical Center
Seattle, Washington, United States, 98122

Sponsors and Collaborators

Swedish Medical Center

Investigators


Principal Investigator:	Arthur M Lam, MD, FRCPC	Swedish Medical Center

More Information


Responsible Party:	Swedish Medical Center
ClinicalTrials.gov Identifier:	NCT01513213 History of Changes
Other Study ID Numbers:	5119S-11
Study First Received:	January 5, 2012
Last Updated:	March 1, 2016
Health Authority:	United States: Institutional Review Board

Keywords provided by Swedish Medical Center:


Arterial cannulation Blood gas Carbon dioxide	Arterial blood Oxygen Oxygen fractions

ClinicalTrials.gov processed this record on September 23, 2016

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