Evaluation of Prostate-specific Membrane Antigen (PSMA)-Based PET Imaging of Primary Prostate Cancer
|ClinicalTrials.gov Identifier: NCT01496157|
Recruitment Status : Unknown
Verified June 2014 by Sidney Kimmel Comprehensive Cancer Center.
Recruitment status was: Active, not recruiting
First Posted : December 21, 2011
Last Update Posted : June 18, 2014
|Condition or disease||Intervention/treatment||Phase|
|Prostate Cancer||Drug: 18F-DCFBC||Phase 1 Phase 2|
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||24 participants|
|Intervention Model:||Single Group Assignment|
|Masking:||None (Open Label)|
|Official Title:||Evaluation of PSMA-based PET as an Imaging Biomarker of Primary Prostate Cancer|
|Study Start Date :||December 2011|
|Estimated Primary Completion Date :||January 2015|
- PET detection of primary prostate cancer [ Time Frame: 24 months ]To compare the detection and sextant localization of primary prostate cancer by DCFBC PET to prostatectomy pathology as determined by tissue step-section analysis in men with biopsy-positive prostate cancer (Gleason score > 4+3=7).
- PET detection of metastatic disease at initial staging [ Time Frame: 24 months ]To compare the detection of bone and nodal metastatic disease by DCFBC PET at initial staging to detection by available conventional imaging modalities (bone scan, CT, MRI) and biopsy pathology.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01496157
|United States, Maryland|
|Johns Hopkins University|
|Baltimore, Maryland, United States, 21287|
|Principal Investigator:||Steve Y. Cho, MD||Johns Hopkins University|