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An Open Prospective Longitudinal Pulmonary-cardiovascular Cohort Study (BIG3)

This study is enrolling participants by invitation only.
Sponsor:
ClinicalTrials.gov Identifier:
NCT01460264
First Posted: October 26, 2011
Last Update Posted: April 20, 2017
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by (Responsible Party):
Region Skane
  Purpose
This is an observational study aiming to identify and validate biomarkers (including imaging and clinical descriptors) for chronic obstructive pulmonary disease (COPD), cardiovascular disease (CVD) and lung cancer.

Condition
Chronic Obstructive Pulmonary Disease Cardiovascular Diseases Lung Cancer

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: BIG3 - An Open Prospective Longitudinal Pulmonary-cardiovascular Cohort Study

Resource links provided by NLM:


Further study details as provided by Region Skane:

Biospecimen Retention:   Samples With DNA
whole blood, serum

Estimated Enrollment: 10000
Actual Study Start Date: October 16, 2013
Estimated Study Completion Date: December 2020
Estimated Primary Completion Date: December 2020 (Final data collection date for primary outcome measure)
Groups/Cohorts
exposed
current daily smokers 100 cigarettes or more during lifetime
unexposed
current non-smokers

  Eligibility

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Ages Eligible for Study:   45 Years to 75 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Community sample,residents in Skåne county Sweden.
Criteria

Inclusion Criteria:

  • 45-75 years
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01460264


Locations
Sweden
Skåne University Hospital
Lund, Sweden, 221 85
Sponsors and Collaborators
Region Skane
Investigators
Study Chair: Ulf Malmqvist, MD, PhD Skane University Hospital
Principal Investigator: David Erlinge, MD, PhD Skane University Hospital
Principal Investigator: Claes-Göran Löfdahl, MD, PhD Skane University Hospital
Principal Investigator: Maria Planck, MD, PhD Skane University Hospital
  More Information

Publications:
Responsible Party: Region Skane
ClinicalTrials.gov Identifier: NCT01460264     History of Changes
Other Study ID Numbers: BIG3-Region_Skane
First Submitted: October 25, 2011
First Posted: October 26, 2011
Last Update Posted: April 20, 2017
Last Verified: April 2017

Keywords provided by Region Skane:
Prospective Cohort Study
Respiratory Function Tests
Computed Tomography
Electrocardiography
Peripheral Arterial Disease

Additional relevant MeSH terms:
Lung Diseases
Cardiovascular Diseases
Lung Diseases, Obstructive
Pulmonary Disease, Chronic Obstructive
Respiratory Tract Diseases