Volumetric Monitoring in Major Lung Surgery (EVLW-PNEUMO)
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ClinicalTrials.gov Identifier: NCT01455766
Recruitment Status :
First Posted : October 20, 2011
Last Update Posted : September 5, 2012
Northern State Medical University
Regional hospital of Arkhangelsk
University of Tromso
Information provided by (Responsible Party):
Vsevolod V. Kuzkov, Northern State Medical University
The hypothesis of this observational single-center clinical study was to explore the volumetric hemodynamic monitoring in the perioperative period in major and risky thoracic intervention. The investigators monitored the changes in the volumes of blood in the central vessels and heart chambers as well as a volume of fluid in pulmonary tissue (i. e. extravascular lung water).
Condition or disease
PneumonectomyAcute Pulmonary Edema
The goal of this observational study is to investigate into changes in volumetric hemodynamic parameters obtained with a technique of transpulmonary indicator dilution after major thoracic intervention, including pneumonectomy and lobar resections. The important parameters of hemodynamics were monitored throughout the intervention and 48 hrs postoperatively, including extravascular lung water index, global end-diastolic volume index, etc.
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Ages Eligible for Study:
18 Years to 80 Years (Adult, Senior)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
The study population includes the patients scheduled for extended thoracic resections (lobar resection and pneumonectomy) due to bronchial cancer or severe destructive pulmonary infection (abscess and/or pneumonia).
Age above 18 and below 80
Confirmed malignant bronchial neoplasm or
Destructive pulmonary infection
Severe pulmonary hypertension
Severe occlusive atherosclerosis of lower extremities