Effect of Temperament, Anxiety and Depression on Immuninity in Colorectal Cancer Patients. Effetti Del Temperamento, Dell'Ansia e Della Depressione Sulla Sopravvivenza Globale e Sulla Risposta Immunitaria Del Paziente Affetto da Adenocarcinoma Colo-Rettale.
Aim of the study is to evaluate if Temperament, Anxiety and Depression can affect Immunity and influence Survival in Colorectal Cancer Patients
|Study Design:||Observational Model: Cohort
Time Perspective: Prospective
|Official Title:||Effect of Temperament, Anxiety and Depression on Immuninity in Colorectal Cancer Patients.|
- Temperament in non-metastatic colorectal cancer patients [ Time Frame: 24 months ] [ Designated as safety issue: Yes ]Evaluation if Temperament can be considered as dependent or indipendent prognostic factor for survival in non-metastatic colorectal cancer patients
Biospecimen Retention: Samples Without DNA
Blood samples for cell-mediated immunity evaluaion
|Study Start Date:||September 2011|
|Study Completion Date:||June 2012|
|Primary Completion Date:||January 2012 (Final data collection date for primary outcome measure)|
120 prospective patients, with non-metastatic colorectal cancer, will be evaluated with questionnaires and auto-questionnaires in order to assess temperament, anxiety and depression. The immunity status will be assessed by a blood sample with the aim to evaluate cell-mediated immunity.
Survivall will be related to level of anxiety/temperament/depression and cell-mediated immunity.
Univariate and multivariate model analisys will be performed in order to evaluate if anxiety/temperament/depression and cell-mediated immunity can be considered as prognostic factors.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01433146
|"Sapienza" University of Rome|
|Rome, Italy, 00100|
|Principal Investigator:||Marco La Torre, MD||"Sapienza" University of Rome|