The Effect of High Dose Salbutamol on Muscle Performance

The recruitment status of this study is unknown because the information has not been verified recently.
Verified March 2011 by Bispebjerg Hospital.
Recruitment status was  Active, not recruiting
University of Copenhagen
Information provided by:
Bispebjerg Hospital Identifier:
First received: August 11, 2011
Last updated: NA
Last verified: March 2011
History: No changes posted
Many athletes use beta2-agonists as treatment of airway hyperresponsiveness during exercise. High dose beta2-agonists may have an ergogenic effect on exercise performance. We hypotheis that the beta2-agonist, salbutamol, taken in high doses can improve muscle power and recovery during exercise in well-trained athletes.

Condition Intervention
Ergogenic Effects of Salbutamol in Healthy Males
Drug: salbutamol
Drug: Placebo

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double Blind (Subject, Caregiver, Investigator)
Official Title: The Effect of High Dose Salbutamol on Dynamic and Isometric Muscle Power and Recovery in Well-trained Males

Resource links provided by NLM:

Further study details as provided by Bispebjerg Hospital:

Primary Outcome Measures:
  • Muscle power

Secondary Outcome Measures:
  • Muscle recovery

Enrollment: 20
Study Start Date: August 2011
Estimated Study Completion Date: August 2013
Estimated Primary Completion Date: August 2012 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Placebo Comparator: Placebo Drug: Placebo
Active Comparator: Salbutamol Drug: salbutamol


Ages Eligible for Study:   18 Years to 45 Years
Genders Eligible for Study:   Male
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • Males
  • age 18-45
  • training frequency > 10 hrs/wk
  • informed consent

Exclusion Criteria:

  • smoker or former smoker
  • chronic diseases, as well as asthma
  • allergy to the study drugs
  • intake of any form of medicin or inhibited drugs during the study
  • use of beta2-agonist 14 days before the intervention
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Please refer to this study by its identifier: NCT01415596

Bispebjerg Hospital
Copenhagen NW, Denmark, DK-2400
Sponsors and Collaborators
Bispebjerg Hospital
University of Copenhagen
  More Information

Responsible Party: Vibeke Backer, Bispebjerg Hospital Identifier: NCT01415596     History of Changes
Other Study ID Numbers: SALMUS2011 
Study First Received: August 11, 2011
Last Updated: August 11, 2011
Health Authority: Denmark: Danish Medicines Agency
Denmark: Good Clinical Practice

Additional relevant MeSH terms:
Adrenergic Agents
Adrenergic Agonists
Adrenergic beta-2 Receptor Agonists
Adrenergic beta-Agonists
Anti-Asthmatic Agents
Autonomic Agents
Bronchodilator Agents
Molecular Mechanisms of Pharmacological Action
Neurotransmitter Agents
Peripheral Nervous System Agents
Physiological Effects of Drugs
Reproductive Control Agents
Respiratory System Agents
Tocolytic Agents processed this record on May 26, 2016