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Physical Activity in Postmenopausal Women

This study has been completed.
Information provided by:
National Taiwan University Hospital Identifier:
First received: July 14, 2011
Last updated: August 16, 2011
Last verified: July 2011
The study is designed to investigate the physical activity and its dose-response relationship in postmenopausal women on the cardiovascular risks and cardiac function.

Condition Intervention
Postmenopausal Disorder
Other: Exercise training

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Open Label
Official Title: Physical Activity and Exercise Dose-response on Cardiovascular Risk Factors in Postmenopausal Women

Resource links provided by NLM:

Further study details as provided by National Taiwan University Hospital:

Primary Outcome Measures:
  • Body mass index (BMI) [ Time Frame: 3 months ]
  • Waist circumference [ Time Frame: 3 months ]
  • Lab data (lipid profile, CRP, insulin resistance) [ Time Frame: 3 months ]
  • QT interval and corrected QT interval (QTc) [ Time Frame: 3 months ]
  • Cardiovascular fitness [ Time Frame: 3 months ]
  • Heart rate recovery after exercise test [ Time Frame: 3 months ]

Secondary Outcome Measures:
  • Myocardial perfusion

Estimated Enrollment: 200
Study Start Date: September 2008
Study Completion Date: July 2010
Primary Completion Date: July 2010 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: moderate exercise training Other: Exercise training
Different dose of exercise training
Experimental: intensive exercise training Other: Exercise training
Different dose of exercise training
No Intervention: Control


Ages Eligible for Study:   40 Years to 80 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • Postmenopausal women aged 40 to 80 years and age matched men without major diseases

Exclusion Criteria:

  • Known cardiac disease, excessive weight change during last year, cancer and mental disorders
  Contacts and Locations
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Please refer to this study by its identifier: NCT01398605

National Taiwan University Hospital
Taipei, Taiwan
Sponsors and Collaborators
National Taiwan University Hospital
Principal Investigator: Ying-Tai Wu, PhD National Taiwan University Hospital
  More Information

Responsible Party: Ying-Tai Wu, School and Graduate Institute of Physical Therapy, College of Medicine, National Taiwan University Identifier: NCT01398605     History of Changes
Other Study ID Numbers: 200709026R
Study First Received: July 14, 2011
Last Updated: August 16, 2011

Keywords provided by National Taiwan University Hospital:
Postmenopausal women
Physical activity
Cardiovascular risks
Cardiac function
Dose-response processed this record on May 23, 2017