Effect Of Piperine In Patients With Oropharyngeal Dysphagia (FIS 2009_2)
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Piperine acts on the oropharyngeal TRPV1, increasing sensory input and the release of substance P. These actions may accelerate the oropharyngeal swallow response, improving the swallowing of dysphagic patients.
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Layout table for eligibility information
Ages Eligible for Study:
18 Years and older (Adult, Older Adult)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
History of swallowing difficulties associated with aging and/or neurological diseases (neurodegenerative or non-progressive neurological diseases)
Study explained and written subject information given
Informed consent signed
Patients suffering idiosyncratic phenomena or who are allergic to any medication, especially iodinated contrast media
Patients suffering major respiratory disease or undergoing any type of surgery in the three months prior to the study
Patients with a background of alcohol dependence or other drug dependence
Currently participating or having participated in another clinical trial during the last 4 weeks prior to the beginning of the study