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Effects of Massage Versus Rest on Hormones

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT01351402
First Posted: May 10, 2011
Last Update Posted: May 10, 2011
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Collaborator:
Gruter Institute
Information provided by:
Claremont Graduate University
  Purpose
This study will investigate the effects of 15 minutes of massage compared to 15 minutes of quiet rest on physiological variables. Specifically, the investigators will measure the effects on levels of the social hormone oxytocin, and on other physiological variables that interact with oxytocin or that may be influenced by massage (including ACTH, Beta-endorphin, and IL-1alpha). The investigators will also investigate whether, in the case of hormones changes, these influence social decision making.

Condition Intervention
Massage Rest Procedure: Massage or Rest

Study Type: Interventional
Study Design: Allocation: Randomized
Masking: Single
Primary Purpose: Basic Science
Official Title: Investigating the Effects of Massage vs. Rest on Oxytocin, ACTH, and B-endorphins

Resource links provided by NLM:


Further study details as provided by Claremont Graduate University:

Primary Outcome Measures:
  • Oxytocin [ Time Frame: Within 5 minutes following experimental manipulation of either 15 minutes massage or rest. ]
    Participants receive a blood draw at baseline and immediately following 15 minutes of massage or rest and oxytocin will be measured from this sample.


Secondary Outcome Measures:
  • Adrenocorticotrophic hormone (ACTH) [ Time Frame: Within 5 minutes following experimental manipulation of either 15 minutes massage or rest. ]
    Participants will receive a blood draw at baseline and immediately following 15 minutes of massage or rest, and ACTH will be measured in these blood samples.

  • Beta-endorphin [ Time Frame: Within 5 minutes following experimental manipulation of either 15 minutes massage or rest. ]
    Participants will receive a blood draw at baseline and immediately following 15 minutes of massage or rest, and B-endorphin will be measured from these samples.

  • Interleukin-1alpha (IL-1a) [ Time Frame: Within 5 minutes following experimental manipulation of either 15 minutes massage or rest. ]
    Participants will receive a blood draw at baseline and immediately following 15 minutes of massage or rest, and IL-1a will be measured from these samples.


Enrollment: 95
Study Start Date: June 2006
Study Completion Date: January 2007
Primary Completion Date: August 2006 (Final data collection date for primary outcome measure)
Intervention Details:
    Procedure: Massage or Rest
    Participants either received 15 minutes of moderate pressure Swedish massage on the upper back, or rested quietly sitting in a chair for 15 minutes.
Detailed Description:
Interested participants will have the experiment explained both verbally and in writing, and asked to give their informed consent in writing. After consent, the participants will be led to a private room for their first 30ml blood draw by a qualified phlebotomist. Participants will then have a second 30ml blood draw.
  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Anyone English speaking and over the age of 18.

Exclusion Criteria:

  • Minors and anyone who has used illicit drugs or alcohol in the last 24 hours.
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01351402


Locations
United States, California
Cassel, UCLA
Los Angeles, California, United States, 90095
Sponsors and Collaborators
Claremont Graduate University
Gruter Institute
  More Information

Responsible Party: Paul J. Zak, Ph.D., Center for Neuroeconomic Studies, Claremont Graduate University
ClinicalTrials.gov Identifier: NCT01351402     History of Changes
Other Study ID Numbers: 00012002
First Submitted: May 6, 2011
First Posted: May 10, 2011
Last Update Posted: May 10, 2011
Last Verified: August 2005

Keywords provided by Claremont Graduate University:
Massage
Rest