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Effects of Massage Versus Rest on Hormones

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ClinicalTrials.gov Identifier: NCT01351402
Recruitment Status : Completed
First Posted : May 10, 2011
Last Update Posted : May 10, 2011
Sponsor:
Collaborator:
Gruter Institute
Information provided by:
Claremont Graduate University

Brief Summary:
This study will investigate the effects of 15 minutes of massage compared to 15 minutes of quiet rest on physiological variables. Specifically, the investigators will measure the effects on levels of the social hormone oxytocin, and on other physiological variables that interact with oxytocin or that may be influenced by massage (including ACTH, Beta-endorphin, and IL-1alpha). The investigators will also investigate whether, in the case of hormones changes, these influence social decision making.

Condition or disease Intervention/treatment
Massage Rest Procedure: Massage or Rest

Detailed Description:
Interested participants will have the experiment explained both verbally and in writing, and asked to give their informed consent in writing. After consent, the participants will be led to a private room for their first 30ml blood draw by a qualified phlebotomist. Participants will then have a second 30ml blood draw.

Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 95 participants
Allocation: Randomized
Masking: Single
Primary Purpose: Basic Science
Official Title: Investigating the Effects of Massage vs. Rest on Oxytocin, ACTH, and B-endorphins
Study Start Date : June 2006
Primary Completion Date : August 2006
Study Completion Date : January 2007

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Hormones
U.S. FDA Resources


Intervention Details:
    Procedure: Massage or Rest
    Participants either received 15 minutes of moderate pressure Swedish massage on the upper back, or rested quietly sitting in a chair for 15 minutes.


Primary Outcome Measures :
  1. Oxytocin [ Time Frame: Within 5 minutes following experimental manipulation of either 15 minutes massage or rest. ]
    Participants receive a blood draw at baseline and immediately following 15 minutes of massage or rest and oxytocin will be measured from this sample.


Secondary Outcome Measures :
  1. Adrenocorticotrophic hormone (ACTH) [ Time Frame: Within 5 minutes following experimental manipulation of either 15 minutes massage or rest. ]
    Participants will receive a blood draw at baseline and immediately following 15 minutes of massage or rest, and ACTH will be measured in these blood samples.

  2. Beta-endorphin [ Time Frame: Within 5 minutes following experimental manipulation of either 15 minutes massage or rest. ]
    Participants will receive a blood draw at baseline and immediately following 15 minutes of massage or rest, and B-endorphin will be measured from these samples.

  3. Interleukin-1alpha (IL-1a) [ Time Frame: Within 5 minutes following experimental manipulation of either 15 minutes massage or rest. ]
    Participants will receive a blood draw at baseline and immediately following 15 minutes of massage or rest, and IL-1a will be measured from these samples.



Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Anyone English speaking and over the age of 18.

Exclusion Criteria:

  • Minors and anyone who has used illicit drugs or alcohol in the last 24 hours.

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01351402


Locations
United States, California
Cassel, UCLA
Los Angeles, California, United States, 90095
Sponsors and Collaborators
Claremont Graduate University
Gruter Institute

Responsible Party: Paul J. Zak, Ph.D., Center for Neuroeconomic Studies, Claremont Graduate University
ClinicalTrials.gov Identifier: NCT01351402     History of Changes
Other Study ID Numbers: 00012002
First Posted: May 10, 2011    Key Record Dates
Last Update Posted: May 10, 2011
Last Verified: August 2005

Keywords provided by Claremont Graduate University:
Massage
Rest