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Treatment of Acne Keloidalis Nuchae (Razor Bumps Behind the Neck) Using UV Light Therapy

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT01328080
First Posted: April 4, 2011
Last Update Posted: March 29, 2017
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Collaborator:
Skin of Color Society
Information provided by (Responsible Party):
Ginette Okoye, MD, Johns Hopkins University
  Purpose
This study is being done to evaluate the effect of targeted UV-B (a component of sunlight) on the treatment of acne keloidalis nuchae (AKN, or razor bumps on the back of the neck). The investigators believe targeted UV-B is a safe and effective way to reduce the appearance of AKN.

Condition Intervention
Acne Keloidalis Nuchae Radiation: Targeted UV-B

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Single Group Assignment
Masking: Single (Investigator)
Primary Purpose: Treatment
Official Title: Improving Acne Keloidalis Nuchae by Inducing Matrix Metalloproteinases in Vivo Using Targeted Ultraviolet-B Irradiation

Resource links provided by NLM:


Further study details as provided by Ginette Okoye, MD, Johns Hopkins University:

Primary Outcome Measures:
  • Percentage Change in Total AKN Lesions From Baseline to Week 16. [ Time Frame: Baseline to Week 16 ]
    To determine if treatment of AKN with targeted ultraviolet B radiation will improve the clinical appearance of lesions.


Enrollment: 11
Study Start Date: February 2011
Study Completion Date: August 2012
Primary Completion Date: August 2012 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: Targeted UV-B (Left)
Targeted UV-B on left side of the scalp.
Radiation: Targeted UV-B
Daavlin Lumera phototherapy device (290-320 nm), dosed by patients' individual minimal erythema dose (MED)
Experimental: Targeted UV-B (Right)
Targeted UV-B on right side of the scalp.
Radiation: Targeted UV-B
Daavlin Lumera phototherapy device (290-320 nm), dosed by patients' individual minimal erythema dose (MED)

  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   Male
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • age 18 or over
  • male gender
  • African-American or other black ethnicity
  • current diagnosis of acne keloidalis nuchae (razor bumps on back of neck)

Exclusion Criteria:

  • allergy to lidocaine or numbing medicine
  • history of increased sensitivity to sunlight, lupus, or porphyria
  • current use of a drug that increases sensitivity to sunlight
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01328080


Locations
United States, Maryland
Johns Hopkins Dept. of Dermatology
Baltimore, Maryland, United States, 21287
Sponsors and Collaborators
Johns Hopkins University
Skin of Color Society
  More Information

Additional Information:
Responsible Party: Ginette Okoye, MD, Assistant Professor, Johns Hopkins University
ClinicalTrials.gov Identifier: NCT01328080     History of Changes
Other Study ID Numbers: NA_00035842
First Submitted: March 31, 2011
First Posted: April 4, 2011
Results First Submitted: April 21, 2014
Results First Posted: June 16, 2014
Last Update Posted: March 29, 2017
Last Verified: February 2017

Additional relevant MeSH terms:
Acne Keloid
Keloid
Collagen Diseases
Connective Tissue Diseases
Acneiform Eruptions
Skin Diseases
Folliculitis
Hair Diseases