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Does a Single Shot Femoral Nerve Block Alone Produce Appropriate Pain Relief?

This study has been completed.
Information provided by:
Hillel Yaffe Medical Center Identifier:
First received: February 20, 2011
Last updated: January 20, 2015
Last verified: February 2011
The aim of this study is to compare the efficacy of the analgesic effect of the preoperative femoral nerve block alone versus combined femoral, sciatic, obturator and lateral femoral cutaneous nerve blocks in patients after TKA in the immediate postoperative period.

Condition Intervention
Post-operative Pain
Drug: Femoral Nerve Block
Drug: Combined nerve blocks
Drug: Patient-controlled analgesia

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double Blind (Participant, Care Provider, Investigator)
Primary Purpose: Treatment
Official Title: Does a Single Shot Femoral Nerve Block Alone Produce Appropriate Pain Relief After Total Knee Arthroplasty or Should an Addition of Sciatic, Obturator and Lateral Femoral Cutaneous Nerve Blocks be Recommended?

Further study details as provided by Hillel Yaffe Medical Center:

Primary Outcome Measures:
  • Efficacy of single short femoral nerve block [ Time Frame: Three days ]

Enrollment: 107
Study Start Date: May 2011
Study Completion Date: December 2013
Primary Completion Date: December 2013 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Active Comparator: Femoral Nerve Block Drug: Femoral Nerve Block
Preoperative Bupivacaine 0.5%, perineurally as single shot
Active Comparator: Combined Nerve Blocks Drug: Combined nerve blocks
Preoperative Bupivacaine 0.5%, perineurally as single shot
Active Comparator: Patient-controlled analgesia Drug: Patient-controlled analgesia
Patient controlled analgesia with morphine

Detailed Description:
Bupivacaine will be used for all the nerve blocks.

Ages Eligible for Study:   30 Years to 85 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Undergoing two TKA
  • Understanding PCA protocol

Exclusion Criteria:

  • Skin infection near injection site
  • Allergy to local analgesics
  • Peripheral neuropathy
  • Coagulopathy
  • Dementia
  • Proven opioid dependency
  Contacts and Locations
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Please refer to this study by its identifier: NCT01303120

Hillel Yaffe Medical Center
Hadera, Israel, 38100
Sponsors and Collaborators
Hillel Yaffe Medical Center
  More Information

Responsible Party: A Stav, MD, Hillel Yaffe Medical Center Identifier: NCT01303120     History of Changes
Other Study ID Numbers: 0021-11-HYMC
Study First Received: February 20, 2011
Last Updated: January 20, 2015

Additional relevant MeSH terms:
Pain, Postoperative
Neurologic Manifestations
Nervous System Diseases
Postoperative Complications
Pathologic Processes
Signs and Symptoms processed this record on May 24, 2017