Measurement of Core Temperatures During Therapeutic Hypothermia (TH)

This study has been completed.
SMG-SNU Boramae Medical Center
Information provided by (Responsible Party):
Jong Hwan Shin, Seoul National University Hospital Identifier:
First received: February 7, 2011
Last updated: July 17, 2015
Last verified: July 2015

The purpose of this study is to determine that the measurements of rectal and bladder temperature are correctly consistent with core temperature by using the pulmonary artery catheter during therapeutic hypothermia; rapid cooling, maintenance, and slow rewarming phase.

Cardiac Arrest

Study Type: Observational
Study Design: Observational Model: Case-Only
Time Perspective: Prospective
Official Title: Core Temperature Measurement in Therapeutic Hypothermia: Tympanic Membrane, Bladder and Rectal Versus Pulmonary Artery Methods

Resource links provided by NLM:

Further study details as provided by Seoul National University Hospital:

Primary Outcome Measures:
  • Difference of core temperature between rectum, bladder, esophagus and pulmonary artery [ Time Frame: During 24 hour ] [ Designated as safety issue: No ]

Enrollment: 20
Study Start Date: February 2011
Study Completion Date: May 2012
Primary Completion Date: February 2012 (Final data collection date for primary outcome measure)
Detailed Description:

The guidelines of therapeutic hypothermia(TH)are rapid cooling, from normothermia to mild hypothermia(32~34 degree), maintenance, and slow rewarming phase. If core temperature maintained below 32 degree during TH, som complications will be developed, such as arrythmia, hypotension, cold diuresis, coagulopathy, and so on. Therefore correct measurement of core temperature during TH is very important process for successful post cardiac arrest care. we will know that rectal or bladder temperature are really reflect the core temperature during TH for post cardiac arrest care, especially rapid cooling phase, maintenance phase, and slow rewarming phase, respectively.


Ages Eligible for Study:   18 Years to 80 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population

Post cardiac arrest care with therapeutic hypothermia


Inclusion Criteria:

  • Out of cardiac arrest patient who is 18 years old.
  • Mean arterial pressure must be over 65 mmHg after return of spontaneous circulation.
  • Family consent to this study.

Exclusion Criteria:

  • In hospital arrest.
  • Arrest due to trauma
  • Arrest due to intracranial hemorrhage.
  • Below 30 degree at initial core temperature.
  • Pregnancy.
  • Family do not agree with our study.
  • Active bleeding patient.
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT01292148

Korea, Republic of
Seoul National University Boramae Hospital
Seoul, Korea, Republic of, 156-707
Sponsors and Collaborators
Seoul National University Hospital
SMG-SNU Boramae Medical Center
Principal Investigator: Shin JongHwan Seoul National University Boramae Hospital
  More Information

No publications provided

Responsible Party: Jong Hwan Shin, Seoul National University, Seoul National University Hospital Identifier: NCT01292148     History of Changes
Other Study ID Numbers: MCT-TH
Study First Received: February 7, 2011
Last Updated: July 17, 2015
Health Authority: Korea: Food and Drug Administration

Keywords provided by Seoul National University Hospital:
resuscitation, hypothermia

Additional relevant MeSH terms:
Heart Arrest
Body Temperature Changes
Cardiovascular Diseases
Heart Diseases
Signs and Symptoms processed this record on October 09, 2015