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Optimization of Preventive Effects of Physical Training (SAusE)

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ClinicalTrials.gov Identifier: NCT01263522
Recruitment Status : Completed
First Posted : December 20, 2010
Last Update Posted : May 10, 2018
Sponsor:
Information provided by (Responsible Party):
Saarland University

Brief Summary:

Health-promoting effects of physical exercise are well-investigated especially for endurance activities. However, for different individuals, positive effects have different sizes, even non-responders are observed. Other forms of training, such as strength training and interval training, are less well investigated. Therefore, a comparative longitudinal training study is warranted to examine differences of preventive effects (outcome measures: ergometric descriptors of physical performance, established risk factors and prognostic factors for cardiovascular diseases) of continuous endurance training, interval training and strength endurance training.

In a second stage, the observed non-responders will perform a different type of training (cross-over). It is expected, that besides a comparative general efficacy evaluation of the three training types, improved recommendations for optimized individualization of training parameters can be formulated.


Condition or disease Intervention/treatment Phase
Primary Prevention, Cardiovascular Risk Factor Management, Size of Response to Training Other: different training programs Other: control condition Not Applicable

Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 266 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Prevention
Official Title: Optimization of Preventive Effects of Physical Training "Saarländische Ausdauer-Etappe (SAusE)"
Actual Study Start Date : December 2010
Actual Primary Completion Date : December 2013
Actual Study Completion Date : December 2013

Arm Intervention/treatment
Experimental: Endurance training Other: different training programs
two different endurance programs and one strength endurance program

Experimental: interval training Other: different training programs
two different endurance programs and one strength endurance program

Experimental: strength endurance training Other: different training programs
two different endurance programs and one strength endurance program

Placebo Comparator: control Other: control condition
unchanged lifestyle




Primary Outcome Measures :
  1. VO2 max [ Time Frame: 6 months ]
    determined during treadmill testing


Secondary Outcome Measures :
  1. resting heart rate [ Time Frame: 6 months ]
  2. resting blood pressure [ Time Frame: 6 months ]
  3. blood lipid profile [ Time Frame: 6 months ]
    ratio: total cholesterol/HDL-cholesterol



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Ages Eligible for Study:   30 Years to 60 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • untrained
  • healthy
  • non-smoking

Exclusion Criteria:

  • Contraindications for physical activity
  • BMI > 30 kg/m2
  • resting blood pressure > 160/100 mmHg
  • diabetes
  • total cholesterol > 300 mg/dl
  • maximal oxygen uptake > 50 ml/min/kg for men and > 45 ml/min/kg for women respectively
  • other complaints or diseases that might interfere with exercise training

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01263522


Locations
Germany
Institute of Sports and Preventive Medicine, Saarland University, Bldg. B 8-2, 66123 Saarbrücken
Saarbrücken, Saarland, Germany, 66123
Sponsors and Collaborators
Saarland University