To Assess the Predictive Value of D-dimer Level on the Occurrence of Cardiovascular Events (COAGFAII)

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT01224574
Recruitment Status : Completed
First Posted : October 20, 2010
Last Update Posted : October 20, 2010
Ministry of Health, France
Information provided by:
Hopital Lariboisière

Brief Summary:
The primary aim of the study was to assess whether D-Dimer level at entry or an increase of D-Dimer level during the follow-up could predict the occurrence of subsequent cardiovascular events in patients with atrial fibrillation.

Condition or disease
Atrial Fibrillation

Detailed Description:
Patients will be followed-up every 4 months with clinical assessment and D-dimer blinded measurement.

Study Type : Observational
Actual Enrollment : 425 participants
Observational Model: Cohort
Time Perspective: Prospective
Official Title: Place Des D-dimères Dans la Prise en Charge Des Patients en Fibrillation Auriculaire : Evaluation de la Valeur prédictive Des D-dimères Sur la Survenue d'événements Thromboemboliques
Study Start Date : January 2001
Actual Primary Completion Date : July 2006
Actual Study Completion Date : July 2007

Resource links provided by the National Library of Medicine

Biospecimen Retention:   Samples Without DNA
No biospecimens are to be retained

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.

Ages Eligible for Study:   18 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Patients with atrial fibrillation encountered in usual care

Inclusion Criteria:

  • atrial fibrillation

Exclusion Criteria:

  • follow-up not possible, poor prognosis within 3 months

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT01224574

Paris, France
Sponsors and Collaborators
Hopital Lariboisière
Ministry of Health, France
Principal Investigator: Isabelle Mahé, MD,PhD Hopital Lariboisière

Responsible Party: Projet Hospitalier de Recherche Clinique Régional, Direction de la Recherche Clinique Identifier: NCT01224574     History of Changes
Other Study ID Numbers: AOR 01 029
First Posted: October 20, 2010    Key Record Dates
Last Update Posted: October 20, 2010
Last Verified: September 2010

Keywords provided by Hopital Lariboisière:
atrial fribrillation, cardiovascular events, aging, D-dimer

Additional relevant MeSH terms:
Atrial Fibrillation
Arrhythmias, Cardiac
Heart Diseases
Cardiovascular Diseases
Pathologic Processes