The Relationship Between Morphology and Virulent Genes of Candida Albicans and Clinical Aspects, Surveillance of Fungemia
|ClinicalTrials.gov Identifier: NCT01211041|
Recruitment Status : Unknown
Verified April 2011 by Taipei Medical University WanFang Hospital.
Recruitment status was: Recruiting
First Posted : September 29, 2010
Last Update Posted : April 25, 2011
Candida albicans is the most common and important clinical fungal pathogen. Our previous surveillance disclosed that fluconazole could induce different morphological changes in clinical strains. Our current study on C. albicans causing candiuria disclosed that renal insufficiency , diabetes mellitus, respiratory failure and uremia were risk factors of treatment failure. However, we also found results of E-test drug susceptible test could not predict outcome. Hence, retrospective analysis of 31 months period, cases that had C. albicans inducing candidemia were reviewed and 60 cases were enrolled for morphological study and potential virulent gene analysis.
This study is designed to clarity the clinical meaning of morphological form and virulent genes on candidemia. To do this study is probably helpful for treatment of candidiasis.
|Condition or disease|
|Candidemia Prognostic Factor and Mycobiological Analysis.|
|Study Type :||Observational|
|Estimated Enrollment :||100 participants|
|Official Title:||The Relationship Between Morphology and Virulent Genes of Candida Albicans and Clinical Aspects, Surveillance of Fungemia|
|Study Start Date :||July 2010|
|Estimated Study Completion Date :||July 2011|
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01211041
|Contact: Tsong-Yih Ou||886-2-29307930 ext firstname.lastname@example.org|
|Taipei Medical University - WanFang Hospital||Recruiting|
|Contact: Tsong-Yih Ou 886-2-29307930 ext 1760 email@example.com|
|Principal Investigator:||Tsong-Yih Ou||Taipei Medical University WanFang Hospital|