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Clinical Research Center for Dementia of South Korea (CREDOS)(or CRCD) (CREDOS)

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified September 2012 by Samsung Medical Center.
Recruitment status was:  Recruiting
Ministry of Health & Welfare, Korea
Information provided by (Responsible Party):
Doh Kwan Kim, Samsung Medical Center Identifier:
First received: September 8, 2010
Last updated: September 26, 2012
Last verified: September 2012
The objective of this study is to present evidence-based medicine for development of clinical practice guideline through prospective study of Alzheimer's disease(AD) and mild cognitive impairment(MCI) in korea

Alzheimer's Disease

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Clinical Research Center for Dementia of South Korea (CREDOS)

Resource links provided by NLM:

Further study details as provided by Samsung Medical Center:

Biospecimen Retention:   Samples With DNA
Serum, plasma and DNAs were prepared

Estimated Enrollment: 800
Study Start Date: November 2005
Estimated Study Completion Date: August 2015
Estimated Primary Completion Date: August 2015 (Final data collection date for primary outcome measure)
Detailed Description:
The specific aims of this study is (1) construction & maintenance of cohort for Alzheimer's disease(AD) and mild cognitive impairment(MCI); (2) study of epidemiology, rate of progression, risk factor, prognostic factor; (3) study of biomarker such as neuropsychological assessment, peripheral & CSF markers, neuroimaging(both structural & functional)

Ages Eligible for Study:   Child, Adult, Senior
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
  1. Patient populatin who is suffering from memory impairment
  2. Normal subjects matched with age and gender

Inclusion Criteria:

  • Alzheimer's disease(AD) and mild cognitive impairment(MCI)will be enrolled in the study.

    1. the diagnostic criteria of Alzheimer's disease(AD) according to DSM IV or NINCDS -ADRDA
    2. the diagnostic criteria of mild cognitive impairment(MCI) A. Memory or other cognitive complaint preferably corroborated by an informant B. Objective memory impairment or other cognitive for age and education C. Largely intact general cognitive function D. Essentially preserved ADL E. Not demented

Exclusion Criteria:

  • Exclusion criteria are current neurological or other psychiatric disorders, as well as a history of epileptic seizures, substantial brain damage or neurosurgical operation, according to established safety criteria.
  Contacts and Locations
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Please refer to this study by its identifier: NCT01198093

Contact: Doh K Kim, Ph.D 82-2-3410-3582

Korea, Republic of
Samsung Medical Center Recruiting
Seoul, Kangnam-Ku, Korea, Republic of, 135-710
Contact: Doh Kwan Kim, M.D and Ph.D    82-2-3410-3582   
Sponsors and Collaborators
Samsung Medical Center
Ministry of Health & Welfare, Korea
Principal Investigator: Doh K KIm, Ph.D Ministry of Health and Welfare
  More Information

Publications automatically indexed to this study by Identifier (NCT Number):
Responsible Party: Doh Kwan Kim, Professor, Samsung Medical Center Identifier: NCT01198093     History of Changes
Other Study ID Numbers: 2005-02-008
Study First Received: September 8, 2010
Last Updated: September 26, 2012

Keywords provided by Samsung Medical Center:
Alzheimer's disease
Mild Cognitive Impairment
cohort study

Additional relevant MeSH terms:
Alzheimer Disease
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Neurodegenerative Diseases
Neurocognitive Disorders
Mental Disorders processed this record on May 25, 2017