Depression and Quality of Life in Chronic Heart Failure Patients and the Caregivers

This study has been completed.

Sponsor:

Information provided by:

National Taiwan University Hospital

ClinicalTrials.gov Identifier:

NCT01197313

First received: September 7, 2010

Last updated: NA

Last verified: September 2010

History: No changes posted

Purpose

Anxiety and depression are often present in patients with chronic heart failure (CHF). This study aimed to evaluate the influence of anxiety and depression on the physical function, disability, and quality of life (QOL) in CHF. This study examined the effects of 8-week home-based exercise on these parameters, and investigated the correlations between these outcome changes.

Condition	Intervention
Chronic Heart Failure (CHF) Anxiety and Depression Quality of Life (QOL) Exercise	Other: Home-based exercise


Study Type:	Interventional
Study Design:	Allocation: Randomized Intervention Model: Parallel Assignment Masking: Single Blind (Subject) Primary Purpose: Treatment
Official Title:	Depression and Quality of Life in Chronic Heart Failure Patients and the Caregivers

Resource links provided by NLM:

MedlinePlus related topics: Anxiety Caregivers Exercise and Physical Fitness Heart Failure

U.S. FDA Resources

Further study details as provided by National Taiwan University Hospital:

Primary Outcome Measures:

Psychologic aspect [ Time Frame: 8 weeks ] [ Designated as safety issue: No ]
Anxiety and depression was measured by Hospital Anxiety and Depression Scale (HADS).
Functional capacity [ Time Frame: 8 weeks ] [ Designated as safety issue: No ]
Functional capacity was assessed by six-minute walk test (6MWT).
Disability level [ Time Frame: 8 weeks ] [ Designated as safety issue: No ]
Groningen Activity Restriction Scale (GARS)
Quality of life [ Time Frame: 8 weeks ] [ Designated as safety issue: No ]
Minnesota Living with Heart Failure Questionnaire (MHFQ) was used to assess quality of life.


Enrollment:	51
Study Start Date:	December 2006
Study Completion Date:	December 2007
Primary Completion Date:	December 2007 (Final data collection date for primary outcome measure)

Arms	Assigned Interventions
Experimental: Exercise	Other: Home-based exercise

Eligibility


Ages Eligible for Study:	20 Years to 80 Years (Adult, Senior)
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No

Criteria

Inclusion Criteria:

Clinical diagnosis of CHF for more than 6 months (NYHA Classes I-III)
Medically stable for at least 3 months

Exclusion Criteria:

Malignancy
Psychiatric disease, primary neuromusculoskeletal or respiratory diseases that affected the assessment of functional or exercise capacity
Changes in medication occurred during the study period

Contacts and Locations

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Please refer to this study by its ClinicalTrials.gov identifier: NCT01197313

Locations


Taiwan
National Taiwan University Hospital
Taipei, Taiwan, 100

Sponsors and Collaborators

National Taiwan University Hospital

Investigators


Principal Investigator:	Ying-Tai Wu, Ph.D	National Taiwan University Hospital

More Information

Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):

Chien CL, Lee CM, Wu YW, Wu YT. Home-based exercise improves the quality of life and physical function but not the psychological status of people with chronic heart failure: a randomised trial. J Physiother. 2011;57(3):157-63. doi: 10.1016/S1836-9553(11)70036-4.


Responsible Party:	Ying-Tai Wu/ Associate professor, School and Graduate Institute of Physical Therapy, College of Medicine, National Taiwan University
ClinicalTrials.gov Identifier:	NCT01197313 History of Changes
Other Study ID Numbers:	9561709097
Study First Received:	September 7, 2010
Last Updated:	September 7, 2010
Health Authority:	Taiwan: Department of Health

Keywords provided by National Taiwan University Hospital:


chronic heart failure (CHF); anxiety and depression; quality of life (QOL); exercise

Additional relevant MeSH terms:


Depression Depressive Disorder Heart Failure Behavioral Symptoms	Mood Disorders Mental Disorders Heart Diseases Cardiovascular Diseases

ClinicalTrials.gov processed this record on September 30, 2016

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