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Johns Hopkins Crohn's Disease and Ulcerative Colitis Study

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified July 2011 by Johns Hopkins University.
Recruitment status was:  Recruiting
Information provided by:
Johns Hopkins University Identifier:
First received: July 23, 2010
Last updated: July 6, 2011
Last verified: July 2011
This research is being done to find out why Inflammatory Bowel Disease (IBD) (i.e., Crohn's disease and ulcerative colitis) occurs in individuals and in families. Recently the investigators and other researchers have found a gene (DNA) that when changed, gives people a higher risk for developing IBD or other inflammatory diseases like IBD. By doing this research, scientists and doctors will study the cells in the blood to see how the gene-change affects the way the blood cells' immune system works.

Inflammatory Bowel Disease

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Prospective
Official Title: Johns Hopkins Crohn's Disease and Ulcerative Colitis Study

Resource links provided by NLM:

Further study details as provided by Johns Hopkins University:

Biospecimen Retention:   Samples With DNA
whole blood, serum

Estimated Enrollment: 2500
Study Start Date: July 1996
Individuals who do not have IBD
Individuals with IBD

  Show Detailed Description


Ages Eligible for Study:   4 Years and older   (Child, Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
IBD patient's are primarily recruited at the Johns Hopkins inpatient and outpatient units. However, individuals contact us by phone, mail or email after hearing about our study

Inclusion Criteria:


  • Patients with IBD and their family members who have or do not have IBD.
  • People that do not have IBD nor have a family member with IBD needed for comparison purposes.
  • The age inclusion criterion for the Multiple Blood Draw (MBD) is 18 years of age or older.


  • Children greater than age 4 with IBD and their family members who have or do not have IBD.
  • People that do not have IBD nor have a family member with IBD needed for comparison purposes.

Exclusion Criteria:

  • The only exclusions are age parameters and health reasons that would preclude their enrollment; such as, for anemic patients. Blood-draws on anemic patients may, in certain medical cases, pose a health risk to them; therefore, we request that if they are anemic that they present a letter from their personal physician giving explicit permission for them to join if at the time it is clinically advisable.
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT01169207

Contact: Patricia Ushry 1(888) 279-4194
Contact: Denise Spears, B.A. (410) 502-5846

United States, Maryland
Johns Hopkins Recruiting
Baltimore, Maryland, United States, 21231
Contact: Patricia Ushry    888-279-4194   
Contact: Denise Spears    (410) 502-5846   
Principal Investigator: Steven R Brant, M.D.         
Sponsors and Collaborators
Johns Hopkins University
Principal Investigator: Steven R Brant, M.D. Johns Hopkins University
  More Information

Responsible Party: Steven R. Brant, M.D., Johns Hopkins University-School of Medicine Identifier: NCT01169207     History of Changes
Other Study ID Numbers: 96-01-31-06
Study First Received: July 23, 2010
Last Updated: July 6, 2011

Keywords provided by Johns Hopkins University:
Inflammatory Bowel Disease
Crohn's Disease
Ulcerative Colitis
Indeterminate Colitis

Additional relevant MeSH terms:
Crohn Disease
Colitis, Ulcerative
Intestinal Diseases
Inflammatory Bowel Diseases
Gastrointestinal Diseases
Digestive System Diseases
Colonic Diseases
Pathologic Processes processed this record on May 25, 2017