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Korea Atherosclerosis Study-3 (KAS3)

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ClinicalTrials.gov Identifier: NCT01168362
Recruitment Status : Completed
First Posted : July 23, 2010
Last Update Posted : October 25, 2013
Sponsor:
Information provided by (Responsible Party):
Soo Lim, Seoul National University Bundang Hospital

Brief Summary:
Multidetector-row Computed Tomography (CT) has been introduced for use in the diagnosis of coronary heart disease. The investigators aimed to characterize coronary artery disease in subjects with cardiovascular risk or not, and in particular plaque natures depending on different status of cardiovascular risk. Especially,the investigators will evaluate the relationships between the pericardial fat and severity of stenosis as well as plaque characteristics using logistic regression models.

Condition or disease
Cardiovascular Diseases Cardiovascular Mortality All-cause Mortality

Study Type : Observational
Actual Enrollment : 4000 participants
Observational Model: Cohort
Time Perspective: Prospective
Official Title: Evaluation of Coronary Artery Disease With Multidetector-Row Cardiac Computed Tomography in Positive Cardiovascular Risk or Not
Study Start Date : February 2006
Primary Completion Date : March 2013
Study Completion Date : May 2013

Resource links provided by the National Library of Medicine

U.S. FDA Resources

Group/Cohort
High risk group
positive cardiovascular risk group
Low risk group
negative cardiovascular risk group



Primary Outcome Measures :
  1. Presence of coronary artery disease [ Time Frame: 5 years ]

Secondary Outcome Measures :
  1. Mortality [ Time Frame: 5 years ]

Biospecimen Retention:   Samples Without DNA
Biochemical paramteres including lipid, glucose, insulin, and other novel cardiometabolic factors


Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 90 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Probability Sample
Study Population
positive cardiovascular risks or not
Criteria

Inclusion Criteria:

  • Korean capable of Multidetector-Row Cardiac Computed Tomography (MDCT)

Exclusion Criteria:

  • malignancy
  • infection
  • shock

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01168362


Locations
Korea, Republic of
Seoul National University Bundang Hospital
Seongnam, Korea, Republic of
Sponsors and Collaborators
Seoul National University Bundang Hospital
Investigators
Principal Investigator: Soo Lim, MD,PHD Seoul National University Bundang Hospital

Responsible Party: Soo Lim, Professor, Seoul National University Bundang Hospital
ClinicalTrials.gov Identifier: NCT01168362     History of Changes
Other Study ID Numbers: M10642140004-06N4214
First Posted: July 23, 2010    Key Record Dates
Last Update Posted: October 25, 2013
Last Verified: October 2013

Keywords provided by Soo Lim, Seoul National University Bundang Hospital:
coronary artery disease
cardiovascular risk
pericardial fat

Additional relevant MeSH terms:
Cardiovascular Diseases
Coronary Artery Disease
Coronary Disease
Myocardial Ischemia
Heart Diseases
Arteriosclerosis
Arterial Occlusive Diseases
Vascular Diseases