Group CBT for Depression and AOD Disorders (BRIGHT2)

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT01154309
Recruitment Status : Completed
First Posted : June 30, 2010
Last Update Posted : November 16, 2011
Behavioral Health Services, Inc.
Information provided by (Responsible Party):

Brief Summary:
The investigators will adapt and test an existing treatment (group CBT for depression) for use in outpatient substance use treatment settings as delivered by trained substance use counselors. The investigators expect that treatment will lead to improved depression and substance use outcomes.

Condition or disease Intervention/treatment Phase
Depression Substance Use Behavioral: Group CBT for Depression and AOD Disorders Phase 1

Detailed Description:

Aim 1. To adapt an existing group therapy (CBT for depression), creating a manualized treatment and accompanying implementation measures and tools for use with clients with persistent depressive symptoms and AOD disorders and to obtain preliminary assessments of the treatment from patient and provider perspectives.

Aim 2. To conduct a pilot test of the revised treatment in which we (a) demonstrate that when the therapy is implemented with fidelity, clinically significant reductions in depressive symptoms and AOD use occur; (b) estimate the likely effect size; and (c) investigate the underlying mechanisms of change, including both cognitive-behavioral and group processes and their relationship to depression and AOD treatment outcomes.

Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 73 participants
Allocation: Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: Group Cognitive Behavioral Therapy for Depression and Alcohol and Other Drug Disorders
Study Start Date : September 2006
Actual Primary Completion Date : September 2009
Actual Study Completion Date : September 2009

Resource links provided by the National Library of Medicine

U.S. FDA Resources

Arm Intervention/treatment
Experimental: 1
Clients are invited to attend 18 group CBT sessions
Behavioral: Group CBT for Depression and AOD Disorders
18 sessions of 2-hour group CBT
No Intervention: 2
Clients receive usual care

Primary Outcome Measures :
  1. Reductions in depressive symptoms as measured by the BDI II [ Time Frame: Post treatment ]
  2. Reductions in AOD use [ Time Frame: Post treatment ]

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • Enrolled in outpatient substance abuse program
  • BDI II score >13
  • Probable alcohol or substance use problem

Exclusion Criteria:

  • Cognitive impairment (Short Blessed > 10)
  • Probably bipolar or schizophrenic disorder

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT01154309

United States, California
Behavioral Health Services, Inc
Gardena, California, United States, 90249
Sponsors and Collaborators
Behavioral Health Services, Inc.
Principal Investigator: Katherine E Watkins, MD, MSHS RAND

Responsible Party: RAND Identifier: NCT01154309     History of Changes
Other Study ID Numbers: R01DA020159 ( U.S. NIH Grant/Contract )
First Posted: June 30, 2010    Key Record Dates
Last Update Posted: November 16, 2011
Last Verified: November 2011

Keywords provided by RAND:
Substance Use
Group Cognitive Behavioral Therapy

Additional relevant MeSH terms:
Depressive Disorder
Behavioral Symptoms
Mood Disorders
Mental Disorders