Effect of Intranasal Mupirocin on Rate of Staphylococcus Aureus Surgical Site Infection Following Cesarean Sections

The recruitment status of this study is unknown because the information has not been verified recently.
Verified June 2010 by Hillel Yaffe Medical Center.
Recruitment status was  Not yet recruiting
Information provided by:
Hillel Yaffe Medical Center
ClinicalTrials.gov Identifier:
First received: May 31, 2010
Last updated: June 28, 2010
Last verified: June 2010

The investigators believe that irradication of nose colonization of staphyloccocus aureus will reduce the incidence of surgical site infections after cesarean section.

Condition Intervention
Surgical Wound Infection
Cesarean Section
Staphylococcus Aureus
Drug: Mupirocin

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Prevention

Resource links provided by NLM:

Further study details as provided by Hillel Yaffe Medical Center:

Primary Outcome Measures:
  • Reduction of the incidence of surgical site infections after cesarean section [ Time Frame: Four years ] [ Designated as safety issue: No ]

Estimated Enrollment: 400
Study Start Date: July 2010
Estimated Study Completion Date: December 2014
Estimated Primary Completion Date: July 2014 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: Intranasal Mupirocin Drug: Mupirocin
Intranasal cream given to patient after confirmation of colonization


Genders Eligible for Study:   Female

Inclusion Criteria:

  • Women assigned to undergo cesarean section

Exclusion Criteria:

  • All others
  Contacts and Locations
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Please refer to this study by its ClinicalTrials.gov identifier: NCT01152593

Hillel Yaffe Medical Center Not yet recruiting
Hadera, Israel, 38100
Contact: Gai Shrem, MD       gais@hy.health.gov.il   
Principal Investigator: Gai Shrem, MD         
Sponsors and Collaborators
Hillel Yaffe Medical Center
  More Information

No publications provided

Responsible Party: Gai Shrem, MD, Hillel Yaffe Medical Center
ClinicalTrials.gov Identifier: NCT01152593     History of Changes
Other Study ID Numbers: HYMC0033-10
Study First Received: May 31, 2010
Last Updated: June 28, 2010
Health Authority: Israel: Ministry of Health

Additional relevant MeSH terms:
Surgical Wound Infection
Wound Infection
Pathologic Processes
Postoperative Complications
Wounds and Injuries
Anti-Bacterial Agents
Anti-Infective Agents
Enzyme Inhibitors
Molecular Mechanisms of Pharmacological Action
Pharmacologic Actions
Protein Synthesis Inhibitors
Therapeutic Uses

ClinicalTrials.gov processed this record on October 06, 2015