Respiratory Quotient and Food Liking, Food Wanting and Food Consumption
The purpose of this study is to observe the influence of carbohydrate-to-fat balance on liking, wanting and food consumption in humans.
Twelve normal-weight men [age: 24 ± 3 y] had completed a randomized 4-condition crossover study. The sessions differed by the composition of the breakfast which was rich in carbohydrates (HCB), low in carbohydrates (LCB), rich in fat (HFB) and low in fat (LFB). The HCB and HFB contained 2072 kJ, while the LCB and LFB contained 565 kJ. Two hours and 20 min later, energy expenditure (EE) and respiratory quotient (RQ) were measured before olfactory liking for 4 foods items and then ad libitum energy intake (EI) during a snack (sweet and fatty toast) were evaluated.
|Study Design:||Observational Model: Case-Crossover
Time Perspective: Cross-Sectional
|Official Title:||Influence of Respiratory Quotient on Food Liking, Food Wanting, Macronutrient Selection and Food Consumption in Humans|
- Respiratory quotient [ Time Frame: 6 months ] [ Designated as safety issue: Yes ]Respiratory quotient is the ratio of CO2 production on oxygen consumption measured in the expiratory flow
- food liking [ Time Frame: 6 months ] [ Designated as safety issue: Yes ]Food liking is the preference for 4 food items smelt
- food wanting [ Time Frame: 6 months ] [ Designated as safety issue: Yes ]food wanting is the selection of 4 kind of toasts during a snack
- food consumption [ Time Frame: 6 months ] [ Designated as safety issue: Yes ]is the amount of food eaten during the snack
|Study Start Date:||October 2008|
|Study Completion Date:||January 2010|
|Primary Completion Date:||August 2009 (Final data collection date for primary outcome measure)|
Behavioral: food preloads
- food intake
In accordance with the carbohydrate-based models of feeding, one may expect that food choices as well as "liking" and "wanting" (the two components of the reward system) could be influenced by glycogen stores and the carbohydrate-to-fat balance. More precisely, one may expect that a high fat oxidation rate could increase liking and wanting carbohydrates to replenish glycogen stores and conversely, that a high carbohydrate oxidation rate could produce the reverse. In order to validate this hypothesis, the present study has been conducted to investigate in humans the influence of the carbohydrate-to-fat oxidation ratio on carbohydrate-to-fat selection and the food reward system.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01122082
|Centre des Sciences du Goût et de l'Alimentation|
|Dijon, France, 21000|
|Study Director:||Luc Penicaud, MD||France: Centre National de la Recherche Scientifique|