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SPECT/CT in the Diagnosis of Dementia (DEMSPET)

This study has been completed.
University of Eastern Finland
Information provided by:
Kuopio University Hospital Identifier:
First received: April 27, 2010
Last updated: NA
Last verified: April 2010
History: No changes posted
Aim of the study is to evaluate whether Tc-99m-ECD-SPECT/CT enhances early diagnosis of dementia in two specific patient groups: (1) patient with mild cognitive impairment, and (2) patient with possible symptoms and signs of frontotemporal dementia. Evaluation of SPECT/CT data is performed both by visual and quantitative voxel-based analyses (Statistical Parametric Mapping). The final diagnosis is based on up to four years clinical follow-up.


Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Prospective
Official Title: SPECT/CT in the Diagnosis of Dementia

Resource links provided by NLM:

Further study details as provided by Kuopio University Hospital:

Primary Outcome Measures:
  • Final diagnosis [ Time Frame: 4 years ]
    (1) controls, (2) stable mild cognitive impairment (MCI), (3)MCI converted to Alzheimers's disease (AD), (4) frontotemporal dementia (FTD), suspected FTD converted to AD, (5) other final diagnoses

Enrollment: 82
Study Start Date: September 2006
Study Completion Date: January 2010
Primary Completion Date: January 2010 (Final data collection date for primary outcome measure)

Ages Eligible for Study:   Child, Adult, Senior
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Probability Sample
Study Population
Subjects with possible/suspected early dementia

Inclusion Criteria (one of these):

  • healthy control
  • mild cognitive impairment (recruited from a population based data)
  • clinically suspected frontotemporal dementia (unset diagnosis)

Exclusion Criteria:

  • unable to be scanned with SPECT/CT
  Contacts and Locations
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Please refer to this study by its identifier: NCT01112501

Kuopio University Hospital
Kuopio, Finland, 70211
Sponsors and Collaborators
Kuopio University Hospital
University of Eastern Finland
  More Information

Responsible Party: Esko Vanninen / Professor, Kuopio University Hospital Identifier: NCT01112501     History of Changes
Other Study ID Numbers: KUH5031339
Study First Received: April 27, 2010
Last Updated: April 27, 2010

Keywords provided by Kuopio University Hospital:

Additional relevant MeSH terms:
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Neurocognitive Disorders
Mental Disorders processed this record on September 21, 2017