The Neuroeconomics of Behavioral Therapies for Adolescent Substance Abuse (Imaging)
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ClinicalTrials.gov Identifier: NCT01093898
Recruitment Status :
First Posted : March 26, 2010
Last Update Posted : March 19, 2018
Dartmouth-Hitchcock Medical Center
National Institutes of Health (NIH)
National Institute on Drug Abuse (NIDA)
Information provided by (Responsible Party):
Catherine Stanger, Dartmouth-Hitchcock Medical Center
This study will measure the brain activity of adolescent substance abusers while they make decisions about their preferences to receive smaller, immediate rewards versus larger delayed rewards. The investigators expect that patterns of brain activity while engaged in this decision making task will predict response to treatment among adolescent substance users. The investigators expect to use the results of this study to develop more effective treatments for adolescent substance abuse
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Ages Eligible for Study:
12 Years to 18 Years (Child, Adult)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
Adolescents recruited into the Marijuana Trial and the Alcohol Trial during the period of the R21 project would participate in a single neuroimaging session as soon after the intake session as possible.
Participants must be 12 to 18 years old and have a parent/guardian who can participate.
Youth must meet either of the following inclusion criteria:
Report using marijuana during the previous 30 days or provide a marijuana-positive urine test, plus meet criteria for Cannabis Abuse or Dependence OR
Meet Diagnostic Statistical Manual (DSM) criteria for Alcohol Abuse or dependence or have had one binge episode, specified by ≥5 drinks in one day, in the past 90 days and report alcohol use in the past 30 days.
Contraindications to MRI including ferromagnetic implants or claustrophobia
Meeting DSM criteria for dependence on illicit drugs other than marijuana or alcohol (use/abuse of other drugs will not be excluded)
Exhibit active psychosis, have severe medical or psychiatric illness limiting participation