Repetitive Transcranial Stimulation (rTMS) in Post Stroke Dysphagia (rTMS AVC)

This study has been completed.
Information provided by (Responsible Party):
University Hospital, Rouen Identifier:
First received: August 14, 2009
Last updated: March 22, 2012
Last verified: March 2012
The aim of this study is to assess if rTMS on healthy hemisphere at one hertz could improve patients with post stroke dysphagia.

Condition Intervention Phase
Device: rTMS
Device: Placebo rTMS
Phase 4

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor)
Primary Purpose: Treatment
Official Title: Effect of Pharyngeal Inhibition Induced by Repetitive Transcranial Stimulation in Post Stroke Dysphagia

Resource links provided by NLM:

Further study details as provided by University Hospital, Rouen:

Primary Outcome Measures:
  • Videofluoroscopy and high resolution manometry [ Time Frame: day 0, day 14, day 30, day45 ] [ Designated as safety issue: No ]

Estimated Enrollment: 30
Study Start Date: March 2009
Study Completion Date: October 2011
Primary Completion Date: April 2011 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Active Comparator: 1
Active rTMS
Device: rTMS
effective and active cortical magnetic stimulations
Placebo Comparator: 2
sham rTMS
Device: Placebo rTMS
non active cortical magnetic stimulation


Ages Eligible for Study:   18 Years to 75 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • dysphagia
  • first episode of stroke

Exclusion Criteria:

  • swallowing disorder before stroke
  • previous episode of stroke
  • MMS < 20 no consent
  Contacts and Locations
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Please refer to this study by its identifier: NCT01081444

Physiology, Rouen University Hospital
Rouen, France, 76031
Sponsors and Collaborators
University Hospital, Rouen
Principal Investigator: Eric VERIN, MD-PhD Rouen University Hospital
  More Information

Responsible Party: University Hospital, Rouen Identifier: NCT01081444     History of Changes
Other Study ID Numbers: 2007/122/HP 
Study First Received: August 14, 2009
Last Updated: March 22, 2012
Health Authority: France: Afssaps - Agence française de sécurité sanitaire des produits de santé (Saint-Denis)

Keywords provided by University Hospital, Rouen:
repetitive transcranial stimulation

Additional relevant MeSH terms:
Deglutition Disorders
Brain Diseases
Cardiovascular Diseases
Central Nervous System Diseases
Cerebrovascular Disorders
Digestive System Diseases
Esophageal Diseases
Gastrointestinal Diseases
Nervous System Diseases
Otorhinolaryngologic Diseases
Pharyngeal Diseases
Vascular Diseases processed this record on May 30, 2016