Early Small Bowel Obstruction Following Laparotomy For Trauma
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT01068340|
Recruitment Status : Completed
First Posted : February 12, 2010
Last Update Posted : May 12, 2016
The formation of intraperitoneal adhesion following abdominal surgery is accepted by clinicians as an inevitable consequence. More than 90% of patients undergoing a surgical procedure in the abdomen will develop intraperitoneal adesions. The incidence however, of small bowel obstruction (SBO) resulting form these adhesions is far lower. To date, it is unknown which risk factors predispose these patients to develop SBO. Several have been proposed, such as age, peritonitis, or surgery for small bowel injury resulting from gunshots. None of them however, has been widely accepted.
During the last 20 years the significant lifetime risks associated with this phenomenon and its impact on the quality of life of patients has been well recognized. In addition, the burden on healthcare resources due to complications caused by adhesions is increasing and medicolegal consequences are rapidly evolving.
Early SBO following laparotomy for trauma is a poorly described entity. A few retrospective, single institution studies with a low number of patients have tried to address this issue. However, these studies either included a subset of trauma patients, i.e. patients sustaining penetrating trauma, or patients undergoing a negative or non-therapeutic laparotomy, or examined only the incidence of SBO requiring surgical intervention. In addition, recent data regarding this issue is lacking, especially after the implementation of the damage control concept and the other advances in trauma surgery.
The aim of this study is to define the incidence of early SBO following laparotomy for trauma and to examine possible risk factors associated with its development.
|Condition or disease|
|Small Bowel Obstruction|
|Study Type :||Observational|
|Actual Enrollment :||571 participants|
|Official Title:||Retrospective Review of the Incidence of Early Small Bowel Obstruction in Patients Undergoing an Exploratory Laparotomy Following Trauma|
|Study Start Date :||January 2010|
|Primary Completion Date :||April 2010|
|Study Completion Date :||June 2010|
Patients who develop small bowel obstruction requiring or not surgical intervention
No SBO Patients
Patients who do not develop small bowel obstruction
- Small Bowel Obstruction not requiring surgical intervention [ Time Frame: 30 days ]
- Ileus [ Time Frame: 30 days ]
- Hospital length of stay [ Time Frame: 30 days ]
- Intensive Care Unit length of stay [ Time Frame: 30 days ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01068340
|United States, California|
|Los Angeles County + University of Southern California Medical Center|
|Los Angeles, California, United States, 90033|
|Principal Investigator:||Demetrios Demetriades, MD, PhD||University of Southern California|