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Altered Faecal Protease Activity in Irritable Bowel Syndrome Patients in China

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ClinicalTrials.gov Identifier: NCT01060527
Recruitment Status : Unknown
Verified January 2010 by Health Science Center of Xi’an Jiaotong University.
Recruitment status was:  Enrolling by invitation
First Posted : February 2, 2010
Last Update Posted : February 2, 2010
Sponsor:
Information provided by:
Health Science Center of Xi’an Jiaotong University

Brief Summary:
Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder haracterised by abdominal pain or discomfort associated with altered bowel habits,while the mechanism is still not understood.Recent advances have conceptualized the faecal supernatants of diarrhoea-predominant IBS have a substantially higher serine protease activity, while in china,almost no studies have reported about protease activity in IBS.

Condition or disease
Irritable Bowel Syndrome

Study Type : Observational
Estimated Enrollment : 60 participants
Observational Model: Case Control
Study Start Date : January 2010

Group/Cohort
IBS-D
IBS-C
Controll




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Ages Eligible for Study:   18 Years to 70 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Probability Sample
Study Population
Outpatients in the second affiliated hospital of xi'an jiaotong university
Criteria

Inclusion Criteria:

  • Patients fulfilling the Rome III criteria for IBS participated in the study -

Exclusion Criteria:

  • Organic gastrointestinal disorders were excluded by detailed blood and stool analyses, serological assays and colonoscopy.

Responsible Party: the second affiliated hospital of xi'an jiaotong university
ClinicalTrials.gov Identifier: NCT01060527     History of Changes
Other Study ID Numbers: xi'an JTU091202
First Posted: February 2, 2010    Key Record Dates
Last Update Posted: February 2, 2010
Last Verified: January 2010

Keywords provided by Health Science Center of Xi’an Jiaotong University:
irritable bowel syndrome,protease activity,China

Additional relevant MeSH terms:
Syndrome
Irritable Bowel Syndrome
Disease
Pathologic Processes
Colonic Diseases, Functional
Colonic Diseases
Intestinal Diseases
Gastrointestinal Diseases
Digestive System Diseases