COVID-19 is an emerging, rapidly evolving situation.
Get the latest public health information from CDC:

Get the latest research information from NIH: Menu

Gene - Exercise Research Study (GERS)

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00976742
Recruitment Status : Completed
First Posted : September 14, 2009
Last Update Posted : September 14, 2009
University of Pittsburgh
Information provided by:
University of Maryland, College Park

Brief Summary:
The investigators hypothesize that the degree to which older generally healthy but sedentary men and women improve a number of cardiovascular (CV) disease risk factors with 6 months of highly-standardized endurance exercise training will be a function of common genetic variations in candidate genes.

Condition or disease Intervention/treatment Phase
Cardiovascular Disease Risk Factors Behavioral: Endurance exercise training Not Applicable

Layout table for study information
Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 225 participants
Allocation: N/A
Intervention Model: Single Group Assignment
Primary Purpose: Prevention
Official Title: Impact of Common Genetic Polymorphisms on CV Disease Risk Factor Changes With Endurance Exercise Training
Study Start Date : June 1998
Actual Primary Completion Date : December 2004

Resource links provided by the National Library of Medicine

Arm Intervention/treatment
Experimental: Endurance Exercise Training Behavioral: Endurance exercise training

Primary Outcome Measures :
  1. Cardiovascular Disease Risk Factors [ Time Frame: ~9 months ]

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.

Layout table for eligibility information
Ages Eligible for Study:   50 Years to 75 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • generally healthy
  • free from CV disease
  • ability to undergo exercise training

Exclusion Criteria:

  • previous history of CV disease

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00976742

Layout table for location information
United States, Maryland
University of Maryland Dept of Kinesiology
College Park, Maryland, United States, 20742-2611
Sponsors and Collaborators
University of Maryland, College Park
University of Pittsburgh
Publications of Results:
Layout table for additonal information
Responsible Party: James Hagberg, PhD, Professor, Principal Investigator, University of Maryland College Park Identifier: NCT00976742    
Other Study ID Numbers: AG17474
First Posted: September 14, 2009    Key Record Dates
Last Update Posted: September 14, 2009
Last Verified: September 2009
Keywords provided by University of Maryland, College Park:
plasma lipoprotein lipids
body composition
glucose tolerance
inflammation markers
insulin sensitivity
coagulation markers
Additional relevant MeSH terms:
Layout table for MeSH terms
Cardiovascular Diseases